Tissue fusion agent

Patent metadata

Field	Value
Publication number	US-10456507-B2
Application number	US-201414765592-A
Country	US
Kind code	B2
Filing date	Mar 5, 2014
Priority date	Mar 8, 2013
Publication date	Oct 29, 2019
Grant date	Oct 29, 2019

Abstract

A tissue fusion agent includes a supporting element and a flock material. A surgical system includes the tissue fusion agent and a tissue fusion instrument. A method of producing the tissue fusion agent includes a) coating a supporting element with an adhesive, and b) flocking the adhesive-coated supporting element with a flock material while the adhesive is moist, adhesive or tacky, or after activation of the adhesive.

First claim

The invention claimed is:

1. A tissue fusion agent comprising a supporting element and a flock material, wherein the supporting element comprises a material which is meltable under the influence of high-frequency alternating current, heat, ultrasound and/or laser irradiation or is formed from such a material, and wherein the flock material connects directly to a surface of the supporting element with no adhesive layer in between the flock material and the surface of the supporting element.

2. The tissue fusion agent according to claim 1 , wherein the supporting element is formed as a two-dimensional planar structure in the form of a disk.

3. The tissue fusion agent according to claim 1 , wherein the supporting element is in the form of a sheet.

4. The tissue fusion agent according to claim 1 , wherein the supporting element is in the form of an annular disk.

5. The tissue fusion agent according to claim 1 , wherein the flock material is in the form of monofilament flock fibers.

6. The tissue fusion agent according to claim 1 , wherein the flock material is in the form of a particulate flock material.

7. The tissue fusion agent according to claim 1 , wherein the supporting element and/or the flock material comprises a resorbable material or is formed from such a material which is preferably selected from the group comprising polyhydroxyalkanoates, polyvinyl alcohol, proteins, extracellular proteins, serum proteins, polysaccharides, mucopolysaccharides, carboxyl group-bearing polysaccharides, amino group-bearing polysaccharides, aldehyde group-bearing polysaccharides, copolymers thereof, salts thereof, stereoisomers, diastereomers thereof, mixtures, and blends thereof.

8. The tissue fusion agent according to claim 1 , wherein the supporting element and/or the flock material comprises a conductivity-increasing or impedance-decreasing additive in the form of a salt.

9. The tissue fusion agent according to claim 8 , wherein the conductivity-increasing or impedance-decreasing additive is selected from the group consisting of alkali metal halide, alkaline earth metal halide, phosphate, alkali metal phosphate, alkaline earth metal phosphate, mixed phosphates and mixtures thereof.

10. The tissue fusion agent according to claim 1 , wherein the supporting element and/or the flock material comprises a conductivity-decreasing additive in the form of a metal.

11. The tissue fusion agent according to claim 1 , wherein the supporting element and/or the flock material comprises an active ingredient selected from the group consisting of biological active ingredient, pharmaceutical active ingredient, medical active ingredient and mixtures thereof.

12. The tissue fusion agent according to claim 1 as surgical tissue fusion agent for use in carrying out anastomoses and/or ligations and/or for tissue closure after resections or partial resections in organs.

13. The tissue fusion agent according to claim 1 for use in the electrosurgical fusion of body tissue.

14. A surgical system comprising a tissue fusion agent according to claim 1 and a tissue fusion instrument, the instrument preferably comprising at least two electrodes for releasing or taking up current, more particularly high-frequency current (HF current).

15. A method of producing a tissue fusion agent according to claim 1 , comprising:
a) coating a supporting element with an adhesive, and
b) flocking the adhesive-coated supporting element with a flock material while the adhesive is moist, adhesive or tacky, or after activation of the adhesive.

16. A method of producing a tissue fusion agent according to claim 1 , comprising:
a) at least partly transferring a supporting element to an adhesive or tacky state, and
b) flocking the at least partly adhesive or tacky supporting element with a flock material.

17. A tissue fusion agent comprising a supporting element and a flock material, wherein the supporting element comprises a material which is meltable under the influence of high-frequency alternating current, heat, ultrasound and/or laser irradiation or is formed from such a material, and wherein the flock material is arranged perpendicular or substantially perpendicular to a surface of the supporting element.

Assignees

• Aesculap Ag

Inventors

• Merckle Christof
• Odermatt Erich

Classifications

• A61L31/148

  Materials at least partially resorbable by the body · CPC title

• A61L24/0015

  Medicaments; Biocides · CPC title

• A61L31/14 Primary

  Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} · CPC title

• A61L31/044

  Collagen · CPC title

• A61B2017/00004

  (bio)absorbable, (bio)resorbable or resorptive · CPC title