Sphingosine kinase type 1 inhibitors
US-9388121-B2 · Jul 12, 2016 · US
Sphingosine kinase type 1 inhibitors and uses thereof
US10456370B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10456370-B2 |
| Application number | US-201816199337-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 26, 2018 |
| Priority date | Apr 29, 2008 |
| Publication date | Oct 29, 2019 |
| Grant date | Oct 29, 2019 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
Provided are inhibitors of sphingosine kinase Type I and their use in the treatment of asthma, among other indications and diseases.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for treating asthma in a patient, comprising: administering to a patient in need of treatment for asthma a compound having the formula 2. The method of claim 1 , wherein the administering step comprises administering to the patient the compound having the formula 3. The method of claim 2 , wherein the administering step comprises administering to the patient 4. A method for treating asthma in a patient, comprising: administering to a patient in need of treatment for asthma a compound having the formula wherein R comprises a straight carbon chain, a branched carbon chain, a straight carbon chain comprising one or more heteroatoms, a branched carbon chain comprising one or more heteroatoms, a cyclic ring, a heterocyclic ring, an aromatic ring, a hetero-aromatic ring, or any combination of the foregoing. 5. The method of claim 4 , wherein R is a straight carbon chain, a branched carbon chain, a straight carbon chain comprising one or more heteroatoms, a branched carbon chain comprising one or more heteroatoms, a cyclic ring, a heterocyclic ring, an aromatic ring, a hetero-aromatic ring, or any combination of the foregoing. 6. The method of claim 5 , wherein R is a straight carbon chain, a branched carbon chain, a straight carbon chain comprising one or more heteroatoms, a branched carbon chain comprising one or more heteroatoms, a cyclic ring, a heterocyclic ring, an aromatic ring, or a hetero-aromatic ring. 7. The method of claim 6 , wherein R is a straight carbon chain, a branched carbon chain, a straight carbon chain comprising one or more heteroatoms, or a branched carbon chain comprising one or more heteroatoms. 8. The method of claim 7 , wherein R is a straight carbon chain or a branched carbon chain. 9. The method of claim 8 , wherein R is a straight carbon chain.
Assignees
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Classifications
having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton · CPC title
- A61K31/135Primary
having aromatic rings {, e.g. ketamine, nortriptyline (methadone A61K31/137)} · CPC title
with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms · CPC title
Antiasthmatics · CPC title
and containing six-membered aromatic rings · CPC title
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Frequently asked questions
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- What does patent US10456370B2 cover?
- Provided are inhibitors of sphingosine kinase Type I and their use in the treatment of asthma, among other indications and diseases.
- Who is the assignee on this patent?
- Enzo Therapeutics Inc, Univ Virginia Commonwealth
- What technology area does this patent fall under?
- Primary CPC classification A61K31/135. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).