Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration

Patent metadata

Field	Value
Publication number	US-10456026-B2
Application number	US-201615098125-A
Country	US
Kind code	B2
Filing date	Apr 13, 2016
Priority date	Dec 15, 2010
Publication date	Oct 29, 2019
Grant date	Oct 29, 2019

Abstract

A system for predicting optical power for an intraocular lens based upon measured biometric parameters in a patient's eye includes: a biometric reader capable of measuring one or more biometric parameters of the patient's eye and obtaining at least one value for at least one of the one or more biometric parameters, and further measuring a representation of a corneal topography of the patient's eye; a processor; and a computer readable medium coupled to the processor and having stored thereon a program that upon execution causes the processor to: receive the at least one value; obtain a corneal spherical aberration (SA) based upon the representation of the corneal topography; and calculate an optimized optical power to obtain a desired postoperative condition by applying the received at least one value and the obtained corneal spherical aberration to a modified regression.

First claim

What is claimed is:

1. A system for predicting optical power for an intraocular lens based upon measured biometric parameters in a patient's eye, the system comprising:
a biometric reader capable of measuring one or more biometric parameters of the patient's eye and obtaining at least one value for at least one of the one or more biometric parameters, and further capable of measuring a representation of a corneal topography of the patient's eye;
a processor; and
a computer readable medium coupled to the processor and having stored thereon a program that upon execution causes the processor to: receive the at least one value; obtain a corneal spherical aberration (SA) based upon the measured representation of the corneal topography; and calculate an optimized optical power to obtain a desired postoperative condition by applying the received at least one value and the obtained corneal spherical aberration to a modified regression, wherein the modified regression is of the form:
optical power= E+F *(Classical Regression Formula)+ D*SA , or
optical power= A+B*AXL+C*K+D*SA,

wherein E, F, D, A, B, and C are empirically derived factors across a plurality of other eyes, wherein AXL is an axial length of the patient's eye, wherein K is an average corneal power in diopters of the patient's eye, wherein the Classical Regression Formula comprises one of the SRK/T, Hoffer Q, Holladay1, Holladay 2, and Haigis regression formulas, and wherein the Classical Regression Formula employs the received at least one value.

2. The system of claim 1 , further comprising a feedback input to said processor for modifying the modified regression in accordance with the optimized optical power.

3. The system of claim 1 , wherein the one or more biometric parameters comprise at least one of: (a) central corneal thickness (CCT), an anterior chamber depth (ACD), a pupil diameter (PD), a white to white distance (WTW), a lens thickness (LT), the axial length (AXL), a retinal layer thickness (RLT), an anterior corneal surface shape, a posterior corneal surface shape, an anterior lens surface shape, a posterior lens surface shape, lens tilt information and lens position information.

4. The system of claim 1 , wherein the one or more biometric parameters comprise at least one of: the axial length, an anterior chamber depth and a corneal power.

5. The system of claim 1 , wherein the desired postoperative condition comprises a postoperative refraction.

6. The system of claim 1 , wherein the biometric reader comprises a corneal topographer.

7. The system of claim 1 , wherein the computer readable medium further has stored thereon a program that upon execution causes the processor to execute a ray tracing algorithm.

8. The system of claim 1 , wherein the biometric reader comprises at least one of an optical wavefront sensor, a corneal topographer, an optical coherence tomographer, a Scheimpflug Imager, a fluorescence imager, a structured lighting imager, a wavefront tomographer, and an ultrasound imager.

9. The system of claim 1 , wherein the program stored on the computer readable medium upon execution causes the processor to employ the modified regression employing measurements of the patient's eye where the patient's eye had previously undergone a refractive procedure.

10. A system for selecting an intraocular lens (IOL) for implantation based upon measured biometric parameters of a patient's eye, comprising:
a biometric reader capable of measuring one or more biometric parameters of the patient's eye and obtaining at least one value for at least one of the one or more biometric parameters, and further capable of measuring a representation of a corneal topography of the patient's eye;
a processor; and
a computer readable medium coupled to the processor and having stored thereon a program that upon execution causes the processor to: receive the at least one value; obtain a corneal spherical aberration (SA) based upon the measured representation of the corneal topography; and calculate an optimized IOL based upon a desired postoperative condition by applying the received at least one value and the obtained corneal spherical aberration to a modified regression, wherein the modified regression is of the form:
optical power= E+F *(Classical Regression Formula)+ D*SA , or
optical power= A+B*AXL+C*K+D*SA,

wherein E, F, D, A, B, and C are empirically derived factors across a plurality of other eyes, wherein AXL is an axial length of the patient's eye, wherein K is an average corneal power in diopters of the patient's eye, wherein the Classical Regression Formula comprises one of the SRK/T, Hoffer Q, Holladay1, Holladay 2, and Haigis regression formulas, and wherein the Classical Regression Formula employs the received at least one value.

11. The system of claim 10 , further comprising a feedback input to said process for modifying the modified regression in accordance with the optimized optical power.

12. The system of claim 10 , wherein the one or more biometric parameters comprise at least one of: a central corneal thickness (CCT), anterior chamber depth (ACD), a pupil diameter (PD), a white to white distance (WTW), a lens thickness (LT), the axial length (AXL), a retinal layer thickness (RLT), an anterior corneal surface shape, a posterior corneal surface shape, an anterior lens surface shape, a posterior lens surface shape, lens tilt information and lens position information.

13. The system of claim 10 , wherein the one or more biometric parameters comprise at least one of: the axial length, an anterior chamber depth and a corneal power.

14. The system of claim 10 , wherein the desired postoperative condition comprises a postoperative refraction.

15. The system of claim 10 , wherein biometric reader comprises a corneal topographer.

16. The system of claim 10 , wherein the computer readable medium further has stored thereon a program that upon execution causes the processor to execute a ray tracing algorithm.

17. The system of claim 10 , wherein the biometric reader comprises at least one of an optical wavefront sensor, a corneal topographer, an optical coherence tomographer, a Scheimpflug Imager, a fluorescence imager, a structured lighting imager, a wavefront tomographer, and an ultrasound imager.

18. The system of claim 10 , wherein the program stored on the computer readable medium upon execution causes the processor to employ the modified regression employing measurements of the patient's eye where the patient's eye had previously undergone a refractive procedure.

19. A system for predicting optical power for an intraocular lens based upon measured biometric parameters of a patient's eye, comprising:
a biometric reader capable of measuring at least two biometric parameters of the patient's eye, including obtaining a first value (VA) for a first biometric parameter and a second value for a second biometric parameter;
a processor; and
a computer readable medium coupled to the processor and having stored thereon a program that upon execution causes the processor to receive the first and second values, and to calculate an optimized optical power to obtain a desired postoperative condition by applying the received first and second values to a modified regression, wherein the modified regression is of the form:
optical power= E+F *(Classical Regression Formula)+ D*VA,

wherein E, F and D are empirically derived factors across a plurality of other eyes, wherein the Classical Regression Formula comprises one of the SRK/T, Hoffer Q, Holladay1, Holladay 2, and

Assignees

• Amo Wavefront Sciences Llc

Inventors

• Neal Daniel R
• Raymond Thomas D
• Copland Richard J
• Xiong Wei
• Farrer Stephen W
• Pulaski Paul D
• Hamrick Daniel R
• Canovas Vidal Carmen
• Artal Pablo

Classifications

• A61F2240/002

  Designing or making customized prostheses · CPC title

• A61B3/0025 Primary

  characterised by electronic signal processing, e.g. eye models · CPC title

• A61F2/16

  Intraocular lenses · CPC title

• A61B3/1005

  for measuring distances inside the eye, e.g. thickness of the cornea (A61B3/11 takes precedence) · CPC title

• A61F2/1637

  Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses · CPC title