Liquid carbon dioxide delivery pump, and supercritical fluid chromatograph provided with the same

Patent metadata

Field	Value
Publication number	US-10451049-B2
Application number	US-201615061214-A
Country	US
Kind code	B2
Filing date	Mar 4, 2016
Priority date	Mar 18, 2015
Publication date	Oct 22, 2019
Grant date	Oct 22, 2019

Abstract

A liquid carbon dioxide delivery pump with a pump head including a pump chamber and a refrigerant channel different from a channel passing through the pump chamber, a circulation channel for refrigerant, a refrigerant pump arranged on the circulation channel, the refrigerant pump for causing the refrigerant to circulate through the circulation channel, and a cooling section arranged on the circulation channel, at a position away from the pump head, the cooling section being configured to cool the refrigerant passing through the circulation channel. The liquid carbon dioxide delivery pump further has a temperature sensor for detecting an ambient temperature of the pump head or a temperature of the pump head, and a refrigerant pump control section for adjusting, based on a detection signal of the temperature sensor, a flow rate of the refrigerant pump such that liquid carbon dioxide flowing through the pump head at a specific temperature.

First claim

What is claimed is:

1. A liquid carbon dioxide delivery pump comprising:
a plunger pump head configured to deliver liquid carbon dioxide, wherein a refrigerant channel is provided inside the plunger pump head and is different from a channel in which liquid carbon dioxide flows;
a circulation channel for refrigerant including the refrigerant channel;
a refrigerant pump that is arranged on the circulation channel, the refrigerant pump being for causing the refrigerant to circulate through the circulation channel;
a cooling section that is arranged on the circulation channel, at a position away from the pump head, the cooling section being configured to cool the refrigerant passing through the circulation channel;
a temperature sensor for detecting an ambient temperature of the pump head or a temperature of the pump head; and
a refrigerant pump control section for adjusting, based on a detection signal of the temperature sensor, a flow rate of the refrigerant pump such that liquid carbon dioxide flowing through the pump head is at a specific temperature.

2. The liquid carbon dioxide delivery pump according to claim 1 ,
wherein the temperature sensor is installed to detect the ambient temperature of the pump head, and
wherein the refrigerant pump control section includes
an information holding section holding information that is obtained in advance as a relationship between the ambient temperature of the pump head and the flow rate of the refrigerant pump when a temperature of liquid carbon dioxide flowing through the pump head becomes constant, and
a flow rate control section for adjusting the flow rate of the refrigerant pump based on the information held in the information holding section and a detection signal of the temperature sensor.

3. The liquid carbon dioxide delivery pump according to claim 2 , wherein the information holding section is an ambient temperature/pump flow rate table holding section that holds 5 the information as a table.

4. The liquid carbon dioxide delivery pump according to claim 1 ,
wherein the temperature sensor is installed to detect the temperature of the pump head, and
wherein the refrigerant pump control section includes a flow rate control section for performing feedback control of the flow rate of the refrigerant pump so that a detected temperature of the temperature sensor becomes constant.

5. A supercritical fluid chromatograph comprising:
a liquid carbon dioxide delivery pump comprising, a plunger pump head configured to deliver liquid carbon dioxide, wherein a refrigerant channel is provided inside the plunger pump head and is different from a channel in which liquid carbon dioxide flows, a circulation channel for refrigerant including the refrigerant channel, a refrigerant pump that is arranged on the circulation channel, the refrigerant pump being for causing the refrigerant to circulate through the circulation channel, a cooling section that is arranged on the circulation channel, at a position away from the pump head, the cooling section being configured to cool the refrigerant passing through the circulation channel, a temperature sensor for detecting an ambient temperature of the pump head or a temperature of the pump head, and a refrigerant pump control section for adjusting, based on a detection signal of the temperature sensor, a flow rate of the refrigerant pump so that liquid carbon dioxide flowing through the pump head is at a specific temperature;
a modifier supply channel for supplying a modifier to a mobile phase channel to which liquid carbon dioxide is supplied by the liquid carbon dioxide delivery pump;
a sample injection section for injecting a sample into an analysis channel at a downstream of a merging section of the mobile phase channel and the modifier supply channel;
a separation column that is arranged at a downstream of the sample injection section;
a back pressure valve that is arranged at a downstream of the separation column, the back pressure valve for maintaining a pressure at which a mobile phase in the separation column is in a supercritical fluid state; and
a detector that is arranged between the separation column and the back pressure valve, or at a downstream of the back pressure valve.

6. The supercritical fluid chromatograph according to claim 5 ,
wherein the temperature sensor is installed to detect the ambient temperature of the pump head, and
wherein the refrigerant pump control section includes
an information holding section holding information that is obtained in advance as a relationship between the ambient temperature of the pump head and the flow rate of the refrigerant pump when a temperature of liquid carbon dioxide flowing through the pump head becomes constant, and
a flow rate control section for adjusting the flow rate of the refrigerant pump based on the information held in the information holding section and a detection signal of the temperature sensor.

7. The supercritical fluid chromatograph according to claim 6 ,
wherein the information holding section is an ambient temperature/pump flow rate table holding section that holds the information as a table.

8. The supercritical fluid chromatograph according to claim 5 ,
wherein the temperature sensor is installed to detect the temperature of the pump head, and
wherein the refrigerant pump control section includes a flow rate control section for performing feedback control of the flow rate of the refrigerant pump so that a detected temperature of the temperature sensor becomes constant.

Assignees

• Shimadzu Corp

Inventors

• Yamamoto Shintaro

Classifications

• F04B53/08 Primary

  Cooling; Heating; Preventing freezing · CPC title

• F04B39/06

  Cooling; Heating; Prevention of freezing · CPC title

• G01N2030/326

  pumps · CPC title

• G01N30/36

  in high pressure liquid systems · CPC title

• F04B15/06

  for liquids near their boiling point, e.g. under subnormal pressure · CPC title