Antimicrobial composition

Patent metadata

Field	Value
Publication number	US-10449137-B2
Application number	US-201616060481-A
Country	US
Kind code	B2
Filing date	Dec 12, 2016
Priority date	Dec 14, 2015
Publication date	Oct 22, 2019
Grant date	Oct 22, 2019

Abstract

The present invention provides an antimicrobial composition comprising a) Thymol; b) Terpineol; c) Niacinamide or its derivatives thereof; and d) a cosmetically acceptable base.

First claim

The invention claimed is:

1. An antimicrobial composition comprising:
a) thymol;
b) terpineol;
c) niacinamide;
d) an antimicrobial peptide; and
e) a cosmetically acceptable base.

2. The composition of claim 1 , wherein the antimicrobial peptide is LL-37.

3. The composition of claim 1 , wherein the amount of thymol is in the range from 0.001 to 5% by weight of the composition.

4. The composition of claim 1 , wherein the amount of terpineol is in the range from 0.001 to 5% by weight of the composition.

5. The composition of claim 1 , wherein the amount of niacinamide is in the range from 0.1 to 5% by weight of the composition.

6. The composition of claim 1 , wherein the amount of antimicrobial peptide is in the range from 0.01 to 10 μg/g of the composition.

7. The composition of claim 1 , wherein the composition is in the form of a leave-on composition.

8. The composition of claim 1 , wherein the composition is in the form of a wash-off composition.

9. The composition of claim 8 , further comprising at least one surfactant.

10. A method of cleaning or disinfecting a surface comprising the step of topically applying an antimicrobial composition on to said surface,
wherein the composition comprises:
a) thymol;
b) terpineol;
c) niacinamide;
d) an antimicrobial peptide; and
e) a cosmetically acceptable base.

11. The method of claim 10 , wherein the antimicrobial composition is in the form of a wash-off composition, and wherein there is an additional step of at least partially removing the applied antimicrobial composition.

12. The method of claim 11 , wherein the step of at least partially removing the antimicrobial composition is carried out in less than 5 minutes after the step of applying the antimicrobial composition on the surface.

13. The composition of claim 1 , wherein the cosmetically acceptable base is a cream, a lotion, a gel, or an emulsion.

14. The composition of claim 1 , wherein the cosmetically acceptable base is present in an amount from 10 to 99.9% by weight of the composition.

15. The composition of claim 1 , wherein the composition further comprises carvacrol.

16. The composition of claim 1 , wherein the antimicrobial peptide comprises defensins, cathelicidin, eosinophil-derived neurotoxin, high-mobility group box protein 1, or a mixture of two or more thereof.

Assignees

• Conopco Inc

Inventors

• Agarwal Khushbu
• Majumdar Amitabha
• Mathapathi Mruthyunjaya Swamy

Classifications

• C11D9/30

  containing nitrogen {(C11D9/225 takes precedence)} · CPC title

• C11D9/26

  containing oxygen {(C11D9/225 takes precedence)} · CPC title

• C11D3/32

  Amides; Substituted amides · CPC title

• C11D3/2037

  Terpenes · CPC title

• A61K8/9767

  Pinaceae [Pine family], e.g. pine or cedar · CPC title