Hyperspectral imaging systems and related methods

Patent metadata

Field	Value
Publication number	US-10448876-B2
Application number	US-201213558888-A
Country	US
Kind code	B2
Filing date	Jul 26, 2012
Priority date	Jul 26, 2011
Publication date	Oct 22, 2019
Grant date	Oct 22, 2019

Abstract

Systems and methods for analyzing sublingual microcirculation perfusion and identifying particular nerve tracts. In exemplary embodiments, a digital micro-mirror device is configured to direct a reflected light to a subject area and a controller is configured to alter a parameter of the reflected light.

First claim

I claim:

1. A method for analyzing microcirculation perfusion of tissue to detect conditions associated with sepsis without contacting a subject area, the method comprising:
directing light to a digital micro-mirror device configured to reflect the light for illuminating a subject area of the tissue;
directing a reflected light from the digital micro-mirror device to illuminate the subject area without contacting the tissue;
dynamically controlling the reflected light from the micro-mirror device to the subject area, wherein a wavelength and a location of the reflected light impinging on the subject area is altered;
detecting a response light reflected from the subject area without contacting the subject area and providing response data related to the response light;
deconvolving the response data relative to the reflected light and providing deconvolved data;
calculating variables including pO 2 levels, pCO 2 levels, and fibrin content of the subject area based on the deconvolved data;
generating an index value, based on the variables for the pO 2 levels, pCO 2 levels, and fibrin content, indicative of changes in a microcirculation perfusion of the subject area for detecting conditions associated with sepsis, wherein the index value is generated using a fuzzy inference system; and
displaying on a display an image of the subject area showing the index value indicative of a change in the microcirculation perfusion of the subject area.

2. The method of claim 1 wherein dynamically controlling the reflected light from the micro-mirror device to the subject area comprises altering the wavelength and the location of the reflected light at least once per second.

3. The method of claim 1 wherein dynamically controlling the reflected light from the micro-mirror device to the subject area comprises altering the wavelength and the location of the reflected light at least twice per second.

4. The method of claim 1 wherein dynamically controlling the reflected light from the micro-mirror device to the subject area comprises altering the wavelength and the location of the reflected light at least three times per second.

5. The method of claim 1 wherein displaying the image of the subject area includes indicating the change in the microcirculation perfusion of the subject area by a different color.

6. The method of claim 1 , further comprising alerting a user when the change in the microcirculation perfusion of the subject area is outside of a defined range.

7. The method of claim 1 , further comprising alerting a user when the microcirculation perfusion of the subject area indicates the subject area has developed systemic inflammatory response syndrome.

Assignees

• Hutchinson George
• Kci Licensing Inc

Inventors

• Hutchinson George

Classifications

• A61B5/1455

  using optical sensors, e.g. spectral photometrical oximeters · CPC title

• A61B5/4041 Primary

  Evaluating nerves condition · CPC title

• A61B5/4542

  Evaluating the mouth, e.g. the jaw · CPC title

• A61B5/441

  Skin evaluation, e.g. for skin disorder diagnosis · CPC title

• A61B5/4076

  Diagnosing or monitoring particular conditions of the nervous system · CPC title