Neurovascular catheter with enlargeable distal end

Patent metadata

Field	Value
Publication number	US-10441745-B2
Application number	US-201715443948-A
Country	US
Kind code	B2
Filing date	Feb 27, 2017
Priority date	Feb 24, 2016
Publication date	Oct 15, 2019
Grant date	Oct 15, 2019

Abstract

A neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the tubular body includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, an outer jacket surrounding the helical coil, and an opening at the distal end. Adjacent windings of the helical coil are spaced progressively further apart in the distal direction. The opening at the distal end of the tubular body is enlargeable from a first inside diameter for transluminal navigation to a second, larger inside diameter to facilitate aspiration of thrombus into the lumen.

First claim

What is claimed is:

1. A neurovascular catheter, comprising:
an elongate flexible tubular body, having a proximal end, a distal end, and a sidewall defining a central lumen, a distal zone of the tubular body comprising:
an opening at the distal end which is enlargeable from a first inside diameter for transluminal navigation to a second, larger inside diameter to facilitate aspiration of thrombus into the central lumen;
a high durometer region of the sidewall and a low durometer region of the sidewall;
a self-expanding stent positioned within the central lumen, wherein the stent is configured to be retained in an under-expanded configuration within the high durometer region and an expanded configuration in the low durometer region, expansion of the stent within the low durometer region being configured to enlarge the opening from the first inside diameter to the second inside diameter;
a tubular inner liner;
a tie layer separated from the central lumen by the inner liner;
a helical coil surrounding the tie layer, adjacent windings of the helical coil spaced progressively further apart in a distal direction; and
an outer jacket surrounding the helical coil,
wherein the stent is moveable along a longitudinal axis defined by the central lumen between the high durometer region and the low durometer region.

2. A neurovascular catheter as in claim 1 , wherein the stent comprises a Nitinol frame.

3. A neurovascular catheter as in claim 1 , wherein the catheter body adjacent the opening at the distal end comprises a hydrophilic blend.

4. A neurovascular catheter as in claim 1 , wherein the tubular liner is formed by dip coating a removable mandrel.

5. A neurovascular catheter as in claim 1 , wherein the tubular liner comprises PTFE.

6. A neurovascular catheter as in claim 1 , wherein the tie layer comprises polyurethane.

7. A neurovascular catheter as in claim 6 , wherein the tie layer has a wall thickness of no more than about 0.005 inches.

8. A neurovascular catheter as in claim 6 , wherein the tie layer extends along at least the most distal 20 cm of the flexible body.

9. A neurovascular catheter as in claim 1 , wherein the helical coil comprises a shape memory material.

10. A neurovascular catheter as in claim 9 , wherein the helical coil comprises Nitinol.

11. A neurovascular catheter as in claim 10 , wherein the Nitinol comprises an Austenite state at body temperature.

12. A neurovascular catheter as in claim 1 , wherein the outer jacket is formed from at least five discrete tubular segments.

13. A neurovascular catheter as in claim 12 , wherein a difference in durometer between a proximal one of the tubular segments and a distal one of the tubular segments is at least about 20 D.

14. A neurovascular catheter as in claim 12 , wherein the difference in durometer between a proximal one of the tubular segments and a distal one of the tubular segments is at least about 30 D.

15. A neurovascular catheter as in claim 1 , wherein the outer jacket is formed from at least nine discrete tubular segments.

16. A neurovascular catheter as in claim 1 , wherein the stent comprises a funnel shape in a self-expanded configuration.

17. A neurovascular catheter as in claim 1 , wherein the stent is configured to straddle the high durometer region and the low durometer region in both the under-expanded configuration in which the opening is set to the first inner diameter and the expanded configuration in which the opening is set to the second inner diameter, the stent being disposed distally further in the low durometer region in the expanded configuration than in the under-expanded configuration.

Assignees

• Incept Llc

Inventors

• Yang Yi
• Khosravi Farhad
• Young Lisa M

Classifications

• A61M25/008

  Strength or flexibility characteristics of the catheter tip · CPC title

• A61B6/501

  for diagnosis of the head, e.g. neuroimaging or craniography · CPC title

• A61M2025/0079

  Separate user-activated means, e.g. guidewires, guide tubes, balloon catheters or sheaths, for sealing off an orifice, e.g. a lumen or side holes, of a catheter · CPC title

• A61B2017/00862

  elastic or resilient · CPC title

• A61M25/01

  Introducing, guiding, advancing, emplacing or holding catheters (A61M25/10 takes precedence) · CPC title