Adjustable chromophore compounds and materials incorporating such compounds

Patent metadata

Field	Value
Publication number	US-10434489-B2
Application number	US-201816014639-A
Country	US
Kind code	B2
Filing date	Jun 21, 2018
Priority date	Apr 2, 2010
Publication date	Oct 8, 2019
Grant date	Oct 8, 2019

Abstract

The present invention is directed to adjustable chromophore compounds and materials (e.g., ophthalmic lens materials) incorporating those compounds. The adjustable chromophore compounds include a chemical moiety that structurally changes upon exposure to predetermined electromagnetic radiation (e.g., two photon radiation) as well as lens materials, particularly intraocular lens materials that incorporate those compounds.

First claim

I claim:

1. An adjustable chromophore selected from the group consisting of:

wherein W is an electron withdrawing moiety;
D is an electron donating moiety; and
Z is a mobilization inhibiting moiety.

2. The adjustable chromophore of claim 1 wherein W is selected from the group consisting of Cl, F, and CF 3 .

3. The adjustable chromophore of claim 1 wherein D is selected from the group consisting of alkyl, alkoxy, and amino groups.

4. The adjustable chromophore of claim 1 wherein Z is selected from the group consisting of unsubstituted or substituted C 4 -C 20 alkyl.

Assignees

• Novartis Ag

Inventors

• Weinschenk Iii Joseph I

Classifications

• B01J19/127

  Sunlight; Visible light · CPC title

• C07D249/20

  with aryl radicals directly attached in position 2 · CPC title

• B29D11/00461

  Adjusting the refractive index, e.g. after implanting · CPC title

• A61L2430/16

  for reconstruction of eye parts, e.g. intraocular lens, cornea · CPC title

• B01J19/123 Primary

  Ultraviolet light · CPC title