Composition and method for orally administering one or more active agents to a pet

Patent metadata

Field	Value
Publication number	US-10434061-B2
Application number	US-201514955932-A
Country	US
Kind code	B2
Filing date	Dec 1, 2015
Priority date	Dec 5, 2014
Publication date	Oct 8, 2019
Grant date	Oct 8, 2019

Abstract

A composition and method for administering an active agent to a pet, such as a dog, a cat or a horse. The composition may comprise a yogurt-based chewable delivery matrix and a plurality of water-soluble film pieces dispersed throughout the chewable delivery matrix. The composition may also comprise a delivery matrix having at least 15% by weight of crude protein and a plurality of water-soluble film pieces dispersed throughout the delivery matrix. The plurality of water-soluble film pieces encompass an active agent therein, wherein the active agent is rapidly released from the composition upon contact with saliva from the pet. At least a portion of the released active agents may be oromucosally absorbed by the pet.

First claim

What is claimed is:

1. A chewable composition formulated for oral delivery to a dog or a cat comprising:
a chewable delivery matrix comprising a yogurt powder, the yogurt powder being at least 3% by weight of the chewable composition, a flavoring agent palatable to the dog or the cat, and water; and
at least about 0.01% by weight of a plurality of water-soluble film pieces dispersed homogeneously throughout the chewable delivery matrix, the plurality of water-soluble film pieces comprise an active agent and a coloring agent therein, the active agent being rapidly releasable from the chewable composition upon contact with saliva from the dog or the cat,
wherein the water in the chewable delivery matrix is in an amount selected for mixing with the plurality of water-soluble film pieces without causing aggregation of the water-soluble film pieces.

2. The composition of claim 1 , wherein the amount of water in the chewable delivery matrix is less than 15% by weight of the chewable composition.

3. The composition of claim 1 , wherein the water-soluble film pieces comprise a film-forming polysaccharide.

4. The composition of claim 3 , wherein the film-forming polysaccharide is a natural starch.

5. The composition of claim 1 , wherein the active agent comprises at least one selected from the group consisting of vitamins, minerals, nutritional supplements, herbal remedies, and pharmaceutical agents.

6. The composition of claim 5 , wherein the active agent comprise at least one selected from the group consisting of anti-plaque agents, anti-inflammatory agents, anti-tumor agents, anesthetics, breath freshening agents, anti-anxiety agents, energizing agents, weight loss agents, vitamins, minerals, and probiotic compositions.

7. The composition of claim 1 , wherein the chewable delivery matrix further comprises the same active agent as the film pieces or an additional active agent.

8. The composition of claim 7 , wherein the additional active agent comprises at least one selected from the group consisting of vitamins, minerals, nutritional supplements, herbal remedies, and pharmaceutical agents.

9. The composition of claim 1 , wherein the chewable delivery matrix further comprises an abrasive agent for mechanically scrubbing against the teeth of the pet.

10. The composition of claim 9 , wherein the active agent comprises sodium hexametaphosphate.

11. The composition of claim 3 , wherein the water-soluble film pieces further comprises at least one of a natural gum, a humectant, and an emulsifier.

12. The composition of claim 1 , wherein the water-soluble film pieces are uniformly sized and shaped.

13. The composition of claim 12 , wherein the water-soluble film pieces are rectangular.

14. The composition of claim 13 , wherein a ratio of a width to a length of the rectangular shape is about 1:1 to about 1:10.

15. The composition of claim 1 , wherein the water-soluble film pieces have a thickness such that the coloring agent does not leech from the water-soluble film pieces into the chewable delivery matrix.

16. The composition of claim 1 , wherein the water-soluble film pieces are substantially free of dietary fiber.

17. The composition of claim 1 , wherein the water-soluble film pieces comprise from about 5% to about 50% by weight of the active agent.

18. The composition of claim 1 , wherein the chewable delivery matrix is substantially free of meat byproducts, gluten or grain.

19. The composition of claim 1 , wherein the chewable delivery matrix further comprises rosemary or rosemary extract.

20. A composition formulated for oral delivery to a dog or a cat comprising:
a delivery matrix comprising at least 15% by weight of crude protein, a flavoring agent palatable to the dog or the cat, and water; and
at least about 0.01% by weight of a plurality of water-soluble film pieces dispersed homogeneously throughout the delivery matrix, the plurality of water-soluble film pieces comprise an active agent and a coloring agent therein, the active agent being rapidly releasable from the composition upon contact with saliva from the dog or the cat,
wherein the water in the delivery matrix is in an amount selected for mixing with the plurality of water-soluble film pieces without causing aggregation of the water-soluble film pieces.

Assignees

• Nestle Sa

Inventors

• Singer Ryan H

Classifications

• A61K31/714

  Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12 · CPC title

• A61K31/7008

  Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine · CPC title

• A61K31/51

  Thiamines, e.g. vitamin B1 · CPC title

• A61K31/4415

  Pyridoxine, i.e. Vitamin B6 (pyridoxal phosphate A61K31/675) · CPC title

• A61K31/198

  Alpha-amino acids, e.g. alanine or edetic acid [EDTA] (betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00) · CPC title