Apparatus and methods for transferring a tissue section
US-2017284904-A1 · Oct 5, 2017 · US
US10422724B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10422724-B2 |
| Application number | US-201715811447-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 13, 2017 |
| Priority date | Nov 14, 2016 |
| Publication date | Sep 24, 2019 |
| Grant date | Sep 24, 2019 |
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A sample sectioning device including a housing having a base member, a cutting mechanism positioned on the base member and operable to cut sections from a sample, a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation, and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation.
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What is claimed is: 1. A sample sectioning device comprising: a housing having a base member; a cutting mechanism positioned on the base member and operable to cut sections from a sample; a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation; and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation, wherein the first member and the second member are each movably connected to the base member and operable to move between a first position in which they are at a first angle with respect to the base member and a second position in which they are at a second angle with respect to the base member, wherein the second angle is greater than the first angle. 2. A sample sectioning device comprising: a housing having a base member; a cutting mechanism positioned on the base member and operable to cut sections from a sample; a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation; and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation, wherein the first member and the second member are operable to move with respect to the base member between a first angle of incline and a second angle of incline, wherein the second angle of incline is approximately 90 degrees and is greater than the first angle of incline. 3. A sample sectioning device comprising: a housing having a base member; a cutting mechanism positioned on the base member and operable to cut sections from a sample; a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation; and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation, wherein the cutting mechanism is operable to slide with respect to the base member, and wherein sliding of the cutting mechanism causes the first member and the second member to move with respect to one another. 4. A sample sectioning device comprising: a housing having a base member; a cutting mechanism positioned on the base member and operable to cut sections from a sample; a sample holder dimensioned to hold a sample and operable to move with respect to the cutting mechanism during a cutting operation; and a waste removal assembly positioned below the cutting mechanism and the sample holder, the waste removal assembly having a first member and a second member that are dimensioned to remove waste produced during the cutting operation, wherein the first member and the second member comprise a position wherein each are at an angle of incline greater than 0 degrees with respect to the base member and comprise an interfacing edge to form a pitched surface below the cutting mechanism and the sample holder. 5. The sample sectioning device of claim 4 wherein the first member and the second member are fixed with respect to one another. 6. The sample sectioning device of claim 4 further comprising: a temperature controlling member coupled to the first member or the second member to control a temperature thereof. 7. A waste removal assembly for a sample sectioning device comprising: a first inclined member coupled to a microtome housing; a second inclined member coupled to a microtome housing; and an actuator movably coupled to the first inclined member and the second inclined member, wherein the actuator is operable to cause a slope of one of the first inclined member or the second inclined member to change. 8. The waste removal assembly of claim 7 wherein the first inclined member and the second inclined member comprise metal plates. 9. The waste removal assembly of claim 7 wherein one of the first inclined member or the second inclined member comprises a plate having an edge that is coupled to the sample sectioning device by a hinge. 10. The waste removal assembly of claim 7 wherein the slope of the first inclined member or the second inclined member is a first slope, and the actuator causes the first inclined member or the second inclined member to change to a second slope, wherein the second slope is greater than the first slope. 11. The waste removal assembly of claim 7 wherein the actuator causes the slope of one of the first inclined member or the second inclined member to change within a range of ninety degrees with respect to horizontal. 12. The waste removal assembly of claim 7 wherein the actuator comprises a cutting mechanism of the sample sectioning device, and wherein a sliding of the cutting mechanism causes the slope of one of the first inclined member or the second inclined member to change. 13. The waste removal assembly of claim 7 wherein the actuator comprises an actuating member and a protrusion, wherein the actuating member slides the protrusion under the first inclined member and the second inclined member to change the slope. 14. The waste removal assembly of claim 7 wherein the actuator is manually operated by a user. 15. The waste removal assembly of claim 7 the actuator is automated. 16. The waste removal assembly of claim 7 further comprising: a thermoelectric cooler (TEC) coupled to the first member or the second member to control a temperature thereof.
Details, e.g. use of specially adapted sources, lighting or optical systems · CPC title
Use of several LED's for spectral resolution · CPC title
electric · CPC title
for sheet material or piles of sheets (B26D7/018 and B26D7/02 take precedence) · CPC title
Means for performing other operations combined with cutting (B26D9/00 takes precedence) · CPC title
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