Drive mechanism for a medicament delivery device

Patent metadata

Field	Value
Publication number	US-10420892-B2
Application number	US-201515518578-A
Country	US
Kind code	B2
Filing date	Oct 1, 2015
Priority date	Oct 22, 2014
Publication date	Sep 24, 2019
Grant date	Sep 24, 2019

Abstract

The present disclosure relates to a drive mechanism for a medicament delivery device according to the disclosure comprises a compression member comprising a first cavity containing a first volume of fluid, said compression member also comprising a second cavity containing a second volume of fluid; a passage for fluid communication between the first cavity and the second cavity; a first movable piston arranged to seal the first cavity; a second movable piston arranged to seal the second cavity; wherein movement of the first movable piston or of the second movable piston, by an applied force, causes a relative change of volume between the first volume of fluid and the second volume of fluid, via a fluid flow through said passage, such that the respective second movable piston or the first movable piston is also moved.

First claim

The invention claimed is:

1. A drive mechanism for a medicament delivery device comprising:
a compression member axially and rotationally fixed within a first housing of the medicament delivery device, where the compression member comprises a first cavity containing a first volume of fluid, said compression member also comprising a second cavity containing a second volume of fluid, and where the compression member is prevented from proximal and distal longitudinal displacement relative to the first housing during all use of the drive mechanism by a connector fixedly attached to a proximal end of the first housing, where the connector comprises an inner connector configured to allow attachment of a second housing containing a medicament container, where inner connector prevents any relevant movement between the first housing and the second housing;
a passage for fluid communication between the first cavity and the second cavity;
a first movable piston arranged to seal the first cavity and to move in the distal direction relative to the compression member when the drive mechanism is activated to expel medicament from the medicament container; and
a second movable piston arranged within an inner tubular sleeve to seal the second cavity and to move in the proximal direction relative to the compression member simultaneously with the first movable piston moving in the distal direction such that a proximal end of the second movable piston acts directly on the medicament container to expel the medicament from the medicament container;
wherein axial movement of the first movable piston or of the second movable piston relative to the compression member, by an applied force, causes a relative change of volume between the first volume of fluid and the second volume of fluid, via a fluid flow through said passage, such that the respective second movable piston or the first movable piston is also moved.

2. The drive mechanism according to claim 1 , wherein the first movable piston is longitudinally movable between a first position and a second position relative to the compression member and wherein the second movable piston is movable between a third and a fourth position relative to the compression member.

3. The drive mechanism according to claim 2 , wherein the first volume of fluid is larger than the second volume of fluid when the first movable piston is in the first position and the second movable piston is in the third position.

4. The drive mechanism according to claim 1 , wherein the drive mechanism further comprises a force member configured to exert the force on the first movable piston.

5. The drive mechanism according to claim 4 , wherein the drive mechanism further comprises an activator member configured to releasably hold said first movable piston in the first position when said first movable piston is under a bias of said force member.

6. The drive mechanism according to claim 5 , wherein the first movable piston is released by a displacement of the activator member in relation to the first movable piston.

7. The drive mechanism according to claim 4 , wherein the force member is arranged between the connector member and the first movable piston.

8. The drive mechanism according to claim 1 , wherein the compression member comprises a distal plate having an outer tubular sleeve arranged coaxially with the inner tubular sleeve and wherein the first cavity is defined by a space between an inner surface of the outer tubular sleeve, the distal plate and an outer surface of the inner tubular sleeve, and wherein the second cavity is defined by the inner surface of the inner tubular sleeve and the distal plate.

9. The drive mechanism according to claim 8 , wherein the passage is defined by a through-hole located at a distal end of the inner tubular sleeve.

10. The drive mechanism according to claim 8 , wherein the drive mechanism further comprises a first seal which is positioned between the first housing and the compression member creating a sealed space between the first housing and the compression member, which space is sealed from ambient pressure.

11. The drive mechanism according to claim 10 , wherein the passage is defined by a first part comprising a first through-hole in the distal plate wherein said through-hole communicates with the first cavity, a second part comprising a channel between the compression member and the first housing through the space sealed by the first seal, and a third part comprising a second through-hole on the distal plate wherein said second through-hole communicates with the second cavity such that the channel between the compression member and the first housing sealed by the first seal communicates through both the first and second through-holes.

12. The drive mechanism according to claim 11 , wherein the first seal comprises the second part of the channel.

13. The drive mechanism according to claim 10 , wherein the first seal is a gasket.

14. A medicament delivery device comprising a drive mechanism according to claim 1 .

15. A drive mechanism for a medicament delivery device comprising
a compression member axially and rotationally fixed within a first housing of the medicament delivery device, where the compression member comprises a first cavity containing a first volume of fluid, said compression member also comprising a second cavity containing a second volume of fluid, and where a connector prevents the compression member from moving distally and proximally relative to the first housing during use of the of the drive mechanism to expel medicament from a container of medicament, where the connector is fixedly attached to a proximal end of the first housing comprises an inner connector configured to allow attachment of a second housing containing the medicament container;
a passage for fluid communication between the first cavity and the second cavity;
a first movable piston arranged to seal the first cavity and to move in the distal direction relative to the compression member when the drive mechanism is activated to expel medicament from the medicament container; and
a second movable piston arranged to seal the second cavity and to move in the proximal direction relative to the compression member when the first movable piston moves in the distal direction;
wherein movement of the first movable piston or of the second movable piston, by an applied force, causes a relative change of volume between the first volume of fluid and the second volume of fluid, via a fluid flow through said passage, such that the respective second movable piston or the first movable piston is also moved,
wherein the first movable piston is longitudinally movable between a first position and a second position relative to the compression member, and wherein the second movable piston is movable between a third and a fourth position relative to the compression member, such that a proximal end of the second movable piston acts directly on the medicament container to expel the medicament from the medicament container.

16. The drive mechanism according to claim 15 , wherein the drive mechanism further comprises a force member configured to exert the force on the first movable piston.

17. The drive mechanism according to claim 16 , wherein the drive mechanism further comprises an activator member configured to releasably hold said first movable piston in the first position when said first movable piston is under a bias of said force member.

18. The drive mechanism according to claim 16 , wherein the force member is arranged between the connector member and the

Assignees

• Carebay Europe Ltd
• Shl Medical Ag

Inventors

• Carpenter Lucas
• Mueller Stephan

Classifications

• A61M2005/3267

  Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body · CPC title

• A61M2005/2013

  triggering of discharging means by contact of injector with patient body · CPC title

• A61M5/3272

  having projections following labyrinth paths · CPC title

• A61M5/3204

  Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices · CPC title

• A61M5/2053 Primary

  Media being expelled from injector by pressurised fluid or vacuum (for infusion A61M5/145, A61M5/155) · CPC title