Therapeutic target for the treatment of cancers and related therapies and methods
US-9763905-B2 · Sep 19, 2017 · US
Therapeutic target for the treatment of cancers and related therapies and methods
US10420742B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10420742-B2 |
| Application number | US-201715704383-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 14, 2017 |
| Priority date | Mar 15, 2013 |
| Publication date | Sep 24, 2019 |
| Grant date | Sep 24, 2019 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of G-coupled protein receptor 40 (GPR40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by cancers, such as melanoma, medullary thyroid carcinoma, malignant peripheral nerve sheath tumors and neuroblastoma, and to reduce the incidence of metastases in such affected subjects.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treating cancer in a subject affected by cancer, wherein the method comprises administering a composition to the subject and thereby treating the cancer, wherein the composition comprises an effective amount of a G-protein coupled receptor 40 (GPR40) agonist; wherein the GPR40 agonist is or a pharmaceutically acceptable salt thereof; and wherein the cancer is a neuroblastoma. 2. The method of claim 1 , wherein the method further comprises administering an effective amount of one or more chemotherapeutic agents to the subject. 3. The method of claim 1 , wherein the subject is a mammal. 4. The method of claim 1 , wherein the subject is a human. 5. The method of claim 1 , wherein the composition is administered orally, subcutaneously, topically, or intravenously to the subject.
Assignees
Inventors
Classifications
having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids · CPC title
the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil · CPC title
- A61K31/202Primary
having three or more double bonds, e.g. linolenic (eicosanoids, e.g. leukotrienes A61K31/557) · CPC title
having one or two double bonds, e.g. oleic, linoleic acids · CPC title
condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US10420742B2 cover?
- Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of G-coupled protein receptor 40 (GPR40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by …
- Who is the assignee on this patent?
- Childrens Medical Ct Corp
- What technology area does this patent fall under?
- Primary CPC classification A61K31/202. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).