Devices, systems, and methods for treating volume overload
US-2024423627-A1 · Dec 26, 2024 · US
US10413237B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10413237-B2 |
| Application number | US-201113997583-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 21, 2011 |
| Priority date | Dec 23, 2010 |
| Publication date | Sep 17, 2019 |
| Grant date | Sep 17, 2019 |
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The present invention relates to a method for calculating or approximating a value representing the relative blood volume (RBV) at a certain point of time, or a value representing the refilling volume of a patient that may be observed or found during or due to a blood treatment of the patient, the method involving considering one or more calculated or measured value(s) reflecting an overhydration level of the patient or an approximation thereof. It relates further to an apparatus and a device for carrying out the present invention, a blood treatment device, digital storage means, a computer program product, and a computer program.
Opening claim text (preview).
The invention claimed is: 1. A method for monitoring a patient during or due to a blood treatment of the patient, the method comprising: obtaining a relative blood volume (RBV_ prior (t)) of the patient at a time point before or during the blood treatment of the patient; determining a normohydrated relative blood volume (RBV_ normohyd ) of the patient based on the relative blood volume (RBV_ prior (t)) and an overhydration level of the patient; wherein the normohydrated relative blood volume (RBV_ normohyd ) at time point t is determined based on an equation: RBV _ normohyd ( t ) = BV _ absolut _ startDialysis BV _ 0 * RBV _ prior ( t ) = BV 0 + OH K _ Guyton BV _ 0 * RBV _ prior ( t ) wherein: BV_ absolute _ startDialysis stands for the absolute blood volume at the beginning of the treatment session; K_ Guyton indicates what portion of the overhydration is comprised within the vessel system; OH stands for the patient's overhydration at the beginning of the blood treatment session; RBV_ prior (t) stands for the patient's relative blood volume; and BV_ 0 stands for the patient's normyhydrated blood volume at the beginning of the blood treatment session; inputting a target range for the normohydrated relative blood volume (RBV_ normohyd ) to meet when the blood treatment is terminated; adjusting an ultrafiltration rate of the blood treatment of the patient based on the determined normohydrated relative blood volume (RBV_ normohyd ); and terminating the blood treatment of the patient based in response to when the determined normohydrated relative blood volume (RBV_ normohyd ) meets the target range for the normohydrated relative blood volume (RBV_ normohyd ). 2. The method according to claim 1 , further comprising determining an absolute start blood volume (BV_ start ) of the patient based on at least one value reflecting a lean mass (LTM) of the patient's body and on at least one value reflecting a fat mass (ATM) of the patient's body. 3. The method according to claim 1 , determining, during the blood treatment of the patient, a plurality of normohydrated relative blood volumes of the patient, each of the normohydrated relative blood volumes based on an absolute blood volume of the patient at a respective point in time during the blood treatment of the patient divided by a blood volume of the patient at a normohydrated state BV 0 . 4. The method according to claim 1 , wherein a target range of the normohydrated relative blood volume (RBV_ normohyd ), to be achieved by the blood treatment of the patient at the end of the blood treatment of the patient is determined. 5. A blood treatment system configured to carry out a method comprising: obtaining a relative blood volume (RBV_ prior (t)) of a patient at a time point before or during a blood treatment of the patient; determining a normohydrated relative blood volume (RBV_ normohyd ) of the patient based on the relative blood volume (RBV_ prior (t)) and an overhydration level of the patient; wherein the normohydrated relative blood volume (RBV_ normohyd ) at time point t is determined based on an equation: RBV _ normohyd ( t ) = BV _ absolut _
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