Stereochemically defined polypropionates and methods for making and using the same
US-2017240560-A1 · Aug 24, 2017 · US
Stereochemically defined polypropionates and methods for making and using the same
US10407439B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10407439-B2 |
| Application number | US-201815906401-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 27, 2018 |
| Priority date | Aug 4, 2014 |
| Publication date | Sep 10, 2019 |
| Grant date | Sep 10, 2019 |
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- Title
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- Abstract
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Abstract
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The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.
First claim
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We claim: 1. A compound of Formula I: 2. The compound of claim 1 having the stereochemistry of the compound of Formula Ia: 3. The compound of claim 1 having the stereochemistry of the compound of Formula Ib: 4. A process for preparing the compound of claim 1 , comprising the steps of: treating a compound of Formula 1: with an oxidizing agent to form the compound of claim 1 . 5. The process of claim 4 , wherein the process forms an intermediate ketone having the following structure of Formula Ia″: 6. The process of claim 4 , wherein the process forms an intermediate ketone having the following structure of Formula Ib″: 7. The process of claim 4 , wherein the compound of Formula 1 is a compound of Formula 1A: and the compound of Formula I has the stereochemistry of a compound of Formula Ia: 8. The process of claim 4 , wherein the compound of Formula 1 is a compound of Formula 1B: and the compound of Formula I has the stereochemistry of a compound of Formula Ib:
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Classifications
Bridged systems · CPC title
Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom · CPC title
- C07D493/22Primary
in which the condensed system contains four or more hetero rings · CPC title
Separation of optically-active compounds · CPC title
Bridged systems · CPC title
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Frequently asked questions
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- What does patent US10407439B2 cover?
- The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.
- Who is the assignee on this patent?
- Eisai R&D Man Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D493/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).