Injectable device for physiological monitoring

Patent metadata

Field	Value
Publication number	US-10405809-B2
Application number	US-201414218594-A
Country	US
Kind code	B2
Filing date	Mar 18, 2014
Priority date	Sep 14, 2007
Publication date	Sep 10, 2019
Grant date	Sep 10, 2019

Abstract

An injectable detecting device is provided for use in physiological monitoring. The device includes a plurality of sensors axially spaced along a body that provide an indication of at least one physiological event of a patient, a monitoring unit within the body coupled to the plurality of sensors configured to receive data from the plurality of sensors and create processed patient data, a power source within the body coupled to the monitoring unit, and a communication antenna external to the body coupled to the monitoring unit configured to transfer data to/from other devices.

First claim

What is claimed is:

1. An injectable device for use in physiological monitoring, comprising:
a body having a shape configured for subcutaneous insertion in a patient;
a plurality of sensors axially spaced along the body that provide an indication of at least one physiological event of the patient;
a power source within the body;
a communication antenna external to the body configured to transfer data to/from other devices, wherein the communication antenna is a self-expanding antenna having a compressed state prior to subcutaneous injection and expanded shape immediately after subcutaneous injection;
a power and communication module within the body and coupled to the communication antenna and the plurality of sensors, wherein the power and communication module selectively supplies power to each of the plurality of sensors and receive sensor data from each of the plurality of sensors.

2. The injectable device of claim 1 , wherein the body is flexible to allow conformance to adjacent tissue anatomy.

3. The injectable device of claim 1 , wherein at least a portion of the body has a drug eluting coating.

4. The injectable device of claim 1 , wherein the self-expanding communication antenna in the compressed state has a cross-sectional profile less than or equal to a cross-sectional profile of the body of the injectable device.

5. The injectable device of claim 1 , wherein the power and communication module manages power consumption by the plurality of sensors.

6. The injectable device of claim 5 , wherein the power and communication module manages power consumption of the plurality of sensors via at least one of modulating drive levels per sensor and modulating a clock speed.

7. The injectable device of claim 5 , wherein the power and communication module manages power consumption by selectively sampling different types of sensors including in the plurality of sensors at different times.

8. The injectable device of claim 7 , wherein the power and communication module continuously samples a first sensor, and monitors a second sensor in order to verify a physiological status flag raised by the first sensor.

9. The injectable device of claim 1 , wherein the plurality of sensors includes two current delivery electrodes and two sensing electrodes for measuring bioimpedance.

10. The injectable device of claim 1 , wherein at least one of the plurality of sensors has openings or an absorbent material configured to sample a hydration level or electrolyte level in a surrounding tissue site of the plurality of sensors.

11. The injectable device of claim 1 , wherein the plurality of sensors further includes at least one activity sensor selected from at least one of, ball switch, accelerometer, minute ventilation, heart rate (HR), bioimpedance noise, skin temperature/heat flux, blood pressure (BP), muscle noise and posture.

12. The injectable device of claim 1 , wherein the power source and the power and communication module are hermetically sealed, and wherein the communication antenna is external to the hermetically sealed portion.

13. The injectable device of claim 1 , wherein the body and antenna are injectable in the patient by at least one of, catheter delivery, blunt tunneling, insertion with a needle, by injection, with a gun or syringe device with a stiffening wire stylet, guidewire, or combination of stylet or guidewire with a catheter.

14. An injectable system for physiological monitoring, the injectable system comprising:
an injector having a first end configured to non-surgically puncture a patient's skin for subcutaneous insertion; and
an injectable device having a rigid state that allows it to be housed within the injector and a flexible state assumed after subcutaneous insertion within the patient, wherein the injectable device includes a self-expanding communication antenna having a compressed state maintained by the injector while the injectable device is housed within the injector prior to subcutaneous injection and expanded shape after subcutaneous injection.

15. The injectable system of claim 14 , wherein the injectable device includes:
a flexible body having a shape configured for subcutaneous insertion in the patient;
a plurality of sensors axially spaced along the flexible body that provide an indication of at least one physiological event of the patient;
a power source within the flexible body;
a power and communication module within the flexible body and coupled to the communication antenna and the plurality of sensors, wherein the power and communication module selectively supplies power to each of the plurality of sensors and receive sensor data from each of the plurality of sensors, wherein the self-expanding communication antenna is external to the flexible body.

16. The injectable system of claim 15 , wherein at least a portion of the body has a drug eluting coating.

17. The injectable device of claim 14 , wherein the body and antenna are injectable in the patient by at least one of, catheter delivery, blunt tunneling, insertion with a needle, by injection, with a gun or syringe device with a stiffening wire stylet, guidewire, or combination of stylet or guidewire with a catheter.

Assignees

• Medtronic Monitoring Inc

Inventors

• Manicka Yatheendhar D
• Amurthur Badri
• Bly Mark
• James Kristofer
• Libbus Imad
• Mazar Scott T
• Wang Jerry S

Classifications

• A61B2562/16

  Details of sensor housings or probes; Details of structural supports for sensors (A61B2560/0462 takes precedence) · CPC title

• A61B5/1118

  Determining activity level · CPC title

• A61B5/7282 Primary

  Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818) · CPC title

• A61B2560/0214

  of power generation or supply · CPC title

• A61B5/076

  Permanent implantation · CPC title