Processing biomass
US-2015353974-A1 · Dec 10, 2015 · US
Polypeptide having the activity of exporting O-acetyl-homoserine
US10400256B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10400256-B2 |
| Application number | US-201615579188-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 3, 2016 |
| Priority date | Jun 4, 2015 |
| Publication date | Sep 3, 2019 |
| Grant date | Sep 3, 2019 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.
First claim
Opening claim text (preview).
The invention claimed is: 1. A polypeptide having the activity of exporting O-acetylhomoserine, wherein at least one amino acid selected from the group consisting of phenylalanine at position 30, leucine at position 95, and phenylalanine at position 165 in the amino acid sequence of SEQ ID NO: 1 is substituted with another amino acid. 2. The polypeptide according to claim 1 , wherein phenylalanine at position 30 in the amino acid sequence of SEQ ID NO: 1 is substituted with any one selected from the group consisting of alanine, tryptophan, leucine, valine, glycine, serine, asparagine, aspartic acid, and histidine; leucine at position 95 in the amino acid sequence of SEQ ID NO: 1 is substituted with any one selected from the group consisting of valine, phenylalanine, alanine, glycine, threonine, asparagine, aspartic acid, and histidine; or phenylalanine at position 165 in the amino acid sequence of SEQ ID NO: 1 is substituted with any one selected from the group consisting of alanine, tryptophan, leucine, valine, glycine, serine, asparagine, aspartic acid, and histidine. 3. The polypeptide according to claim 1 , wherein valine at position 1 in the amino acid sequence of SEQ ID NO: 1 is further substituted with methionine. 4. The polypeptide according to claim 1 , wherein the polypeptide is selected from the group consisting of amino acid sequences of SEQ ID NOS: 133, 134, 137, 138, 141, and 142.
Assignees
Inventors
Classifications
Methionine; Cysteine; Cystine · CPC title
- C12P13/06Primary
Alanine; Leucine; Isoleucine; Serine; Homoserine · CPC title
- C12N15/70Primary
Vectors or expression systems specially adapted for E. coli · CPC title
- C07K14/245Primary
Escherichia (G) · CPC title
Aspartate-semialdehyde dehydrogenase (1.2.1.11) · CPC title
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Frequently asked questions
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- What does patent US10400256B2 cover?
- The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.
- Who is the assignee on this patent?
- Cj Cheiljedang Corp
- What technology area does this patent fall under?
- Primary CPC classification C12P13/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).