Container for specimen preparation

Patent metadata

Field	Value
Publication number	US-10386277-B2
Application number	US-201414908034-A
Country	US
Kind code	B2
Filing date	Jul 25, 2014
Priority date	Jul 26, 2013
Publication date	Aug 20, 2019
Grant date	Aug 20, 2019

Abstract

A mechanism for collecting a trace of a biological sample to be used for a biological sample analysis, and for preparing a diluted solution of the sample. A container for specimen preparation includes: a biological sample collecting device; and a container for sample dilution. The biological sample collecting device includes: a capillary tube having openings formed at both ends thereof; and a support member for supporting the capillary tube. The container for sample dilution includes: an opening; and a swirl flow generating member formed on an inner wall of the container for sample dilution. The capillary tube of the biological sample collecting device is arranged inside the container for sample dilution by the support member.

First claim

The invention claimed is:

1. A container for specimen preparation, comprising:
a biological sample collecting device; and
a container for sample dilution,
the biological sample collecting device comprising:
a capillary tube having openings formed at both ends thereof; and
a support member for supporting the capillary tube,

the container for sample dilution comprising:
an opening;
a swirl flow generating member formed integrally in an inner wall of the container for sample dilution where the inner wall has differing thicknesses; and
an outer wall of the container where the outer wall is curved and independent of the shape of the swirl flow generating member,

the capillary tube of the biological sample collecting device being arranged inside the container for sample dilution by the support member so that a position of an upper end of the capillary tube is level with or lower than a position of an upper end of the swirl flow generating member,
the capillary tube of the biological sample collecting device being arranged inside the container for sample dilution by the support member so that a position of the capillary tube is offset from a central axis of the container for sample dilution.

2. The container for specimen preparation according to claim 1 , wherein the biological sample collecting device further comprises a fixing member for fixing the biological sample collecting device to the container for sample dilution, so that the capillary tube of the biological sample collecting device is arranged in the container for sample dilution.

3. The container for specimen preparation according to claim 1 , further comprising a lid for closing the opening of the container for sample dilution.

4. The container for specimen preparation according to claim 3 , wherein a fixing member comprises the lid.

5. The container for specimen preparation according to claim 3 , wherein the lid has a hole formed therein to allow passage of an injection tube for injecting a liquid into the container for sample dilution, or the lid comprises a film capable of being pierced through by the injection tube.

6. The container for specimen preparation according to claim 1 , further comprising a guide for arranging the capillary tube of the biological sample collecting device at a desired position in the container for sample dilution.

7. The container for specimen preparation according to claim 1 , further comprising an engaging member for retaining the container for specimen preparation in a predetermined direction on a rack.

8. A biological sample collecting device, comprising:
a capillary tube having openings formed at both ends thereof; and
a support member for supporting the capillary tube,
wherein the capillary tube of the biological sample collecting device is arranged inside a container by the support member so that a position of an upper end of the capillary tube is level with or lower than a position of an upper end of a swirl flow generating member, the container comprising an opening and the swirl flow generating member formed integrally in an inner wall of the container where the inner wall has differing thicknesses and an outer wall of the container where the outer wall is curved and independent of the shape of the swirl flow generating member, and
wherein the capillary tube of the biological sample collecting device is arranged inside the container by the support member so that a position of the capillary tube is offset from a central axis of the container.

9. A container for sample dilution, comprising:
an opening;
a swirl flow generating member formed integrally in an inner wall of the container for sample dilution where the inner wall has differing thicknesses; and
an outer wall of the container where the outer wall is curved and independent of the shape of the swirl flow generating member,
wherein a capillary tube of a biological sample collecting device is arranged inside the container for sample dilution by a support member so that a position of an upper end of the capillary tube is level with or lower than a position of an upper end of the swirl flow generating member, the biological sample collecting device comprising the capillary tube having openings formed at both ends thereof, and the support member for supporting the capillary tube,
the capillary tube of the biological sample collecting device being arranged inside the container for sample dilution by the support member so that a position of the capillary tube is offset from a central axis of the container for sample dilution.

10. The container for specimen preparation according to claim 1 , wherein the swirl flow generating member comprises at least one of:
a slope formed to extend from a side surface of the inner wall of the container for sample dilution toward a bottom of the inner wall of the container for sample dilution;
a conical protrusion formed on the side surface of the inner wall of the container for sample dilution or on a center of the bottom of the inner wall of the container for sample dilution;
a plurality of blade-form protrusions formed on the bottom of the inner wall of the container for sample dilution;
a spiral protrusion formed to extend from the side surface of the inner wall of the container for sample dilution toward the bottom of the inner wall of the container for sample dilution; and
a recess formed at an off-center position to the bottom of the container for sample dilution.

11. The container for sample dilution according to claim 9 , wherein the swirl flow generating member comprises at least one of:
a slope formed to extend from a side surface of the inner wall of the container for sample dilution toward a bottom of the inner wall of the container for sample dilution;
a conical protrusion formed on the side surface of the inner wall of the container for sample dilution or on a center of the bottom of the inner wall of the container for sample dilution;
a plurality of blade-form protrusions formed on the bottom of the inner wall of the container for sample dilution;
a spiral protrusion formed to extend from the side surface of the inner wall of the container for sample dilution toward the bottom of the inner wall of the container for sample dilution; and
a recess formed at an off-center position to the bottom of the container for sample dilution.

12. The container for specimen preparation according to claim 1 , wherein the capillary tube is disposed at a distal aspect of the support member for supporting the capillary tube so that a dimension of the capillary tube is perpendicular to the distal aspect of the support member.

13. The container for specimen preparation according to claim 1 , wherein the capillary tube is disposed at a distal aspect of the support member for supporting the capillary tube so that a dimension of the capillary tube is parallel to the distal aspect of the support member.

14. The container for specimen preparation according to claim 1 , wherein the capillary tube of the biological sample collecting device is arranged inside the container for sample dilution by the support member so that the capillary tube is lower than an upper end of the swirl flow generating member.

15. The container for specimen preparation according to claim 1 , wherein the swirl flow generating member is formed integrally in an inner wall of a distal portion of the container for sample dilution where the inner wall has differing thicknesses.

16. The container for specimen preparation according to claim 1 , wherein the swirl flow generating member is formed integrally on a bottom, a side, or a c

Assignees

• Sekisui Medical Co Ltd
• Sekisui Techno Molding Co Ltd

Inventors

• Taira Hiroaki
• Nemoto Yuriko
• Yotani Takuya
• Tominaga Satoru

Classifications

• G01N1/10

  in the liquid or fluent state {(burettes, pipettes B01L3/02; sampling of ground water E02D1/06; metering by volume of fluids or fluent solid material G01F11/00, G01F13/00)} · CPC title

• B01L3/50825

  Closing or opening means, corks, bungs · CPC title

• B01L2300/0851

  Bottom walls · CPC title

• B01L2400/086

  using baffles or other fixed flow obstructions · CPC title

• A61B5/150022

  for capillary blood or interstitial fluid · CPC title