Membrane with performance enhancing multi-level macroscopic cavities

Patent metadata

Field	Value
Publication number	US-10384168-B2
Application number	US-201515325766-A
Country	US
Kind code	B2
Filing date	Jul 15, 2015
Priority date	Jul 18, 2014
Publication date	Aug 20, 2019
Grant date	Aug 20, 2019

Abstract

The present invention relates to a micro-porous filtration membrane with performance enhancing multi-level macro-scopic cavities as well as a method for producing the same.

First claim

The invention claimed is:

1. A micro-porous filtration membrane, comprising a plurality of multi-level macroscopic discrete cavities extending from a first main surface of the membrane into the porous membrane which differ from the micropores constituting the micro-porous membrane and which are irregularly arranged within the membrane, wherein the penetration depth of the plurality of macroscopic cavities within the porous membrane is not uniform, the average penetration depth of the cavities into the membrane being from 30 to 80% of the total thickness of the membrane, wherein the individual diameter of the cavities measured at the opening of the membrane's first main surface is from 10 to 1000 μm, and wherein the diameter of the cavities is substantially the same throughout 50% of the penetration depth.

2. The micro-porous filtration membrane according to claim 1 , wherein the shape of the plurality of cavities is a cylindrical, cone, or pyramidal shape.

3. The micro-porous filtration membrane according to claim 1 , wherein the individual diameter of the cavities has a standard deviation of 20% or more from the arithmetic mean of the cavity diameter.

4. The micro-porous filtration membrane according to claim 1 having a surface porosity of from 15 to 50%.

5. The micro-porous filtration membrane according to claim 1 , wherein the filter material is formed using a porous polymer membrane made from at least one of polyether sulfone, polyamide, a cellulose derivative, cellulose mixed ester, cellulose acetate, cellulose nitrate, cellulose, polypropylene, polyethylene, polytetrafluoroethylene, expanded polytetrafluoroethylene, polyvinylidene difluoride or polyvinyl chloride.

6. A method for producing a micro-porous filtration membrane according to claim 1 , comprising the following steps:
providing a micro-porous filtration membrane having a first and second main surface, and
modifying the first main surface of the membrane so as to mechanically, chemically and/or thermally form a plurality of multi-level macroscopic discrete cavities extending from a first main surface of the membrane into the porous membrane.

7. The method according to claim 6 , wherein the step of modifying the first main surface of the membrane is carried out by spiking using a plurality of sharp needles.

8. A method of using the micro-porous filtration membrane according to claim 1 in sterilizing processes in food and beverage filtration of water, wine, beer or biopharmaceutical filtration of cell and bacteria nutrition media or clarification and purification filtration of cell and bacteria broths.

9. A method for improving the throughput and/or flow rate of a micro-porous filtration membrane, comprising the step of modifying a first main surface of the membrane so as to mechanically, chemically and/or thermally form a plurality of multi-level macroscopic discrete cavities extending from a first main surface of the membrane into the porous membrane which differ from the micropores constituting the micro-porous membrane and which are irregularly arranged within the membrane, wherein the penetration depth of the plurality of macroscopic cavities within the porous membrane is not uniform, the average penetration depth of the cavities into the membrane being from 30 to 80% of the total thickness of the membrane, wherein the individual diameter of the cavities measured at the opening of the membrane's first surface is from 10 to 1000 and wherein the diameter of the cavities is substantially the same throughout 50% of the penetration depth.

Assignees

• Sartorius Stedim Biotech Gmbh

Inventors

• Mundrigi Ashok
• Gowda Jahnavi
• Mundlamuri Ramesh
• Loewe Thomas
• Linne Holger
• Handt Sebastian

Classifications

• B01D2325/08

  Patterned membranes · CPC title

• C12H1/063

  Separation by filtration · CPC title

• B01D67/0086 Primary

  Mechanical after-treatment · CPC title

• B01D67/0083

  Thermal after-treatment · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title