Membrane module apparatus, packaging body, liquid treatment system, steam sterilization method and system constructing method

Patent metadata

Field	Value
Publication number	US-10384166-B2
Application number	US-201415103598-A
Country	US
Kind code	B2
Filing date	Dec 25, 2014
Priority date	Dec 27, 2013
Publication date	Aug 20, 2019
Grant date	Aug 20, 2019

Abstract

Provided is a membrane module apparatus capable of allowing an aseptic connection member to be applicable to a hollow fiber membrane module and avoiding the need for a user to perform a sterilization treatment. A membrane module apparatus includes: a hollow fiber membrane module to be filled with a liquid during steam sterilization; thermoplastic tubes, being aseptic connection members, for aseptically connecting the membrane module apparatus to another duct; connecting tubes for connecting liquid ports of the hollow fiber membrane module respectively to the thermoplastic tubes; and closure members capable of pinching and closing the connecting tubes. The connecting tubes have heat resistance to the steam sterilization. An expansion member is connected to a liquid port of the hollow fiber membrane module.

First claim

What is claimed is:

1. A membrane module apparatus to be subjected to steam sterilization, comprising:
a hollow fiber membrane module filled with a liquid;
an aseptic connection member configured to aseptically connect the membrane module apparatus to a duct, the aseptic connection member comprising a first aseptic connector having a first connecting surface and a second aseptic connector having a second connecting surface, the first aseptic connector and the second aseptic connector being fixed to each other;
a sealing tape interposed between the first connecting surface and the second connecting surface, wherein the sealing tape is configured to be pulled out while maintaining the aseptic state;
a connecting tube for connecting a liquid port of the hollow fiber membrane module and the aseptic connection member to each other; and
a closure member capable of pinching and closing the connecting tube,
wherein the connecting tube has heat resistance to the steam sterilization.

2. The membrane module apparatus according to claim 1 , wherein the closure member is configured to apply pressure to the connecting tube via a screw mechanism to close the connecting tube.

3. The membrane module apparatus according to claim 1 , further comprising an opening/closing part that opens and closes an internal space, the internal space being located on the aseptic connection member side with respect to the closure member, in the connecting tube relative to an atmosphere.

4. The membrane module apparatus according to claim 1 , further comprising a fixing apparatus for fixing at least one of the connecting tube and the aseptic connection member.

5. The membrane module apparatus according to claim 4 , wherein the fixing apparatus includes a fixing plate and a fixture for fixing at least one of the connecting tube and the aseptic connection member onto the fixing plate.

6. The membrane module apparatus according to claim 1 , wherein the connecting tube is made of a silicon resin or a fluorine resin.

7. The membrane module apparatus according to claim 1 , wherein the hollow fiber membrane module has a plurality of liquid ports, and at least one of the liquid ports is connected to an expansion member that expands due to an increase in an internal pressure of the hollow fiber membrane module during the steam sterilization.

8. The membrane module apparatus according to claim 7 , wherein:
the hollow fiber membrane module has two liquid ports communicating with an inside of a hollow fiber membrane and two liquid ports communicating with an outside of the hollow fiber membrane; and
one of the liquid ports communicating with the outside of the hollow fiber membrane is connected to the expansion member and the other three liquid ports are connected to the connecting tube.

9. The membrane module apparatus according to claim 1 , wherein the aseptic connection member is a thermoplastic tube configured to be thermally welded.

10. A packaging body containing a membrane module apparatus, the packaging body hermetically packaging the membrane module apparatus according to any one of claims 1 - 9 .

11. The packaging body containing a membrane module apparatus according to claim 10 , wherein the packaging body provides packaging with an air permeable member.

12. A liquid treatment system including the duct and the membrane module apparatus according to any one of claims 1 - 9 , wherein the aseptic connection member of the membrane module apparatus is aseptically connected to the duct.

Assignees

• Asahi Kasei Medical Co Ltd

Inventors

• Fukada Seiji

Classifications

• B01D2321/08

  Use of hot water or water vapor · CPC title

• B01D65/02

  Membrane cleaning or sterilisation {; Membrane regeneration} · CPC title

• B01D65/022 Primary

  Membrane sterilisation · CPC title

• B01D2313/13

  Specific connectors · CPC title

• B01D63/02 Primary

  Hollow fibre modules · CPC title