Image generating apparatus and image generating method

Patent metadata

Field	Value
Publication number	US-10379336-B2
Application number	US-201815868580-A
Country	US
Kind code	B2
Filing date	Jan 11, 2018
Priority date	Jan 24, 2017
Publication date	Aug 13, 2019
Grant date	Aug 13, 2019

Abstract

An image generating apparatus is provided with a first light source and a second light source, an image sensor, a mask including a light-transmitting part and a light-blocking part, and a dark image processing unit. The image sensor acquires a first image of the material when illuminated by the first light source, and acquires a second image of the material when illuminated by the second light source. The image sensor includes a first pixel region and a second pixel region. The light-blocking part is positioned between the first pixel region and the first light source. The light-blocking part is positioned between the first pixel region and the first light source. The dark image processing unit uses first pixel information corresponding to a first pixel region in the first image and second pixel information corresponding to a second pixel region in the second image to generate a third image.

First claim

What is claimed is:

1. An image generating apparatus that generates an image of a translucent material, comprising:
a first light source;
a second light source positioned a certain distance away from the first light source;
an image sensor on which the material is disposed;
a mask including a light-transmitting part that transmits light from the first light source and the second light source, and a light-blocking part that blocks the light, the mask being positioned between the image sensor, and the first light source and the second light source; and
a processing circuit, wherein
the image sensor
acquires a first image of the material when illuminated by the first light source,
acquires a second image of the material when illuminated by the second light source,
the image sensor includes a first pixel region and a second pixel region,
the light-blocking part is positioned between the first pixel region and the first light source,
the light-blocking part is positioned between the second pixel region and the second light source, and
the processing circuit
uses first pixel information corresponding to the first pixel region in the first image and second pixel information corresponding to the second pixel region in the second image to generate a third image.

2. The image generating apparatus according to claim 1 , wherein
the material is an embryo including a cell, and
the processing circuit
specifies a region having a brightness equal to or greater than a first threshold value in the third image as a region where the cell is positioned.

3. The image generating apparatus according to claim 2 , wherein
the processing circuit
uses the third image and the region where the cell is positioned to generate a fourth image emphasizing the region where the cell is positioned.

4. The image generating apparatus according to claim 1 , wherein
the material is an embryo including multiple cells, and
the processing circuit
(a1) extracts multiple cell regions having a brightness equal to or greater than a first threshold value in the third image,
(a2) determines whether or not the brightness of each of the multiple cells regions is within a second range, and
(a3) outputs the determination result.

5. The image generating apparatus according to claim 4 , wherein
the processing circuit
in (a3),
outputs a determination result indicating that the multiple cells are normal in a case in which the brightness of each of the multiple cell regions is within the second region, and
outputs a determination result indicating that the multiple cells are abnormal in a case in which the brightness of each of the multiple cell regions is outside the second region.

6. The image generating apparatus according to claim 1 , wherein
the material is an embryo including a cell, and
the processing circuit
(b1) extracts a cell region having a brightness equal to or greater than a first threshold value in the third image, and
(b2) computes a density of the cell on a basis of the brightness of the cell region.

7. An image generating method that generates an image of a translucent material using
a first light source,
a second light source positioned a certain distance away from the first light source,
an image sensor on which the material is disposed, and
a mask including a light-transmitting part that transmits light from the first light source and the second light source, and a light-blocking part that blocks the light, the mask being positioned between the image sensor, and the first light source and the second light source,
the image sensor including a first pixel region and a second pixel region,
the light-blocking part being positioned between the first pixel region and the first light source, and
the light-blocking part being positioned between the second pixel region and the second light source,

the image generating method comprising:
(a) acquiring, with the image sensor, a first image of the material when illuminated by the first light source;
(b) acquiring, with the image sensor, a second image of the material when illuminated by the second light source; and
(c) using first pixel information corresponding to the first pixel region in the first image and second pixel information corresponding to the second pixel region in the second image to generate a third image.

8. An image generating apparatus, comprising:
a light source including a first light source and a second light source;
an image sensor, including first pixels and second pixels;
a mask having a transmission part and a shield including a first shield and a second shield, the mask being located between the light source and the image sensor; and
a processing circuit, wherein
the first shield is located on a light path for first light that is emitted from the first light source and travels straight from the first light source to the first pixels,
the second shield is located on a light path for second light that is emitted from the second light source and travels straight from the second light source to the second pixels,
the processing circuit generates an image of an object provided between the mask and the image sensor using information detected by the first pixels during a first time period when the first light source emits light and information detected by the second pixels during a second time period when the second light source emits light, and
the first time period and the second time period are not overlapped.

Assignees

• Panasonic Ip Man Co Ltd

Inventors

• Kato Yumiko
• Sawada Yoshihide
• Mukaigawa Yasuhiro
• Funatomi Takuya
• Kubo Hiroyuki
• Kuniyoshi Fusataka

Classifications

• G06V20/693 Primary

  Acquisition · CPC title

• G02B21/365 Primary

  Control or image processing arrangements for digital or video microscopes (G02B21/361, G02B21/362 take precedence) · CPC title

• G06F18/23213

  with fixed number of clusters, e.g. K-means clustering · CPC title

• G06V10/141

  Control of illumination · CPC title

• G06K9/0014

  Physics · mapped topic