Rare earth material-binding peptide and use thereof

Patent metadata

Field	Value
Publication number	US-10377795-B2
Application number	US-201515113287-A
Country	US
Kind code	B2
Filing date	Jan 21, 2015
Priority date	Jan 22, 2014
Publication date	Aug 13, 2019
Grant date	Aug 13, 2019

Abstract

A binding agent is capable of binding to rare earth materials such as rare earths and inorganic compounds thereof. A rare earth material-binding agent includes a peptide capable of binding to a rare earth material including a rare earth and a rare earth inorganic compound.

First claim

The invention claimed is:

1. A method for producing a complex of a rare earth material-binding agent and a rare earth material, comprising:
bringing the rare earth material-binding agent comprising a peptide capable of binding to the rare earth material into contact with the rare earth material to form the complex,
wherein
the rare earth material comprises at least one rare earth atom selected from the group consisting of lanthanum (La), lanthanum (La) ion, cerium (Ce), cerium (Ce) ion, neodymium (Nd), neodymium (Nd) ion, samarium (Sm), samarium (Sm) ion, gadolinium (Gd), gadolinium (Gd) ion, terbium (Tb), terbium (Tb) ion, dysprosium (Dy), dysprosium (Dy) ion, holmium (Ho), holmium (Ho) ion, erbium (Er), and erbium (Er) ion, and
the peptide has an amino acid sequence represented by Leu-Trp-Gly-Asp/Glu-Val-Ser/Asn-Asp/Glu-Leu/Val-Asp/Glu-Phe/Leu-Leu.

2. The method according to claim 1 , wherein the peptide is a cyclic peptide.

3. The method according to claim 1 , wherein the rare earth material comprises dysprosium and a dysprosium ion, and the binding agent binds to the dysprosium ion and an oxide of dysprosium.

4. The method according to claim 1 , wherein the peptide has a label substance bound thereto.

5. The method according to claim 1 , wherein the rare earth atom is at least one rare earth ion selected from the group consisting of lanthanum (La) ion, cerium (Ce) ion, neodymium (Nd) ion, samarium (Sm) ion, gadolinium (Gd) ion, terbium (Tb) ion, dysprosium (Dy) ion, holmium (Ho) ion, and erbium (Er) ion.

6. The method according to claim 5 , wherein the complex is an inorganic compound comprising the at least one rare earth ion.

7. The method according to claim 5 , wherein the at least one rare earth ion is dysprosium (Dy) ion.

8. The method according to claim 6 , wherein the at least one rare earth ion is dysprosium (Dy) ion.

Assignees

• Toyota Chuo Kenkyusho Kk

Inventors

• Hatanaka Takaaki
• Ishida Nobuhiro

Classifications

• C01F17/206

  oxide or hydroxide being the only anion · CPC title

• C01P2004/64

  Nanometer sized, i.e. from 1-100 nanometer · CPC title

• C01P2002/85

  by XPS, EDX or EDAX data · CPC title

• C07K7/06 Primary

  having 5 to 11 amino acids · CPC title

• C22B59/00

  Obtaining rare earth metals · CPC title