System and method for the validation and quality assurance of computerized contours of human anatomy

Patent metadata

Field	Value
Publication number	US-10376715-B2
Application number	US-201514700592-A
Country	US
Kind code	B2
Filing date	Apr 30, 2015
Priority date	Aug 8, 2013
Publication date	Aug 13, 2019
Grant date	Aug 13, 2019

Abstract

A system and method for validating the accuracy of delineated contours in computerized imaging using statistical data for generating assessment criterion that define acceptable tolerances for delineated contours, with the statistical data being conditionally updated and/or refined between individual processes for validating delineated contours to thereby adjust the tolerances defined by the assessment criterion in the stored statistical data, such that the stored statistical data is more closely representative of a target population. In an alternative embodiment, a system and method for validating the accuracy of delineated contours in computerized imaging using machine learning for assessing delineated contours, with the machine learning training data being used to generate geometric attributes, and the geometric attributes used to construct intra- and interstructural geometric attribute distribution models to automatically detect contouring errors. The present invention may be used to facilitate, as one example, radiation therapy.

First claim

What is claimed is:

1. A system for validating accuracy of delineated contours in computerized imaging, comprising:
a storage unit including one or more approved radiation therapy contours and a patient specific radiation therapy contour; and
a processor programmed to:
receive the one or more approved radiation therapy contours,
calculate a geometric attribute of the one or more approved radiation therapy contours,
construct assessment criterion parameters using machine learning methods,
receive the patient specific radiation therapy contour from the storage unit,
calculate a patient specific radiation therapy contour geometric attribute using the patient specific radiation therapy contour, and
detect contouring error by fitting the geometric attribute of the patient specific radiation therapy contour to the assessment criterion parameters.

2. The system of claim 1 , wherein the processor is further programmed to update the assessment criterion parameters using the one or more approved radiation therapy contours.

3. The system of claim 1 , further comprising a graphical display unit programmed to at least one of visualize the contouring error by using a software graphical user interface and using graphics techniques to present one or more differences between the patient specific radiation therapy contour and the assessment criterion parameters.

4. The system of claim 3 , wherein the graphical display unit is further programmed to allow clinicians to directly modify one or more reported incorrect radiation therapy contours by moving control points of the one or more reported incorrect radiation therapy contours.

5. The system of claim 1 , wherein the patient specific radiation therapy contour corresponds to a patient receiving adaptive radiation therapy.

6. The system of claim 1 , wherein the patient specific radiation therapy contour corresponds to a patient receiving on-line adaptive radiation therapy.

7. The system of claim 1 , wherein the processor is further programmed to add, in the storage unit, the patient specific radiation therapy contour to the one or more approved radiation therapy contours.

8. The system of claim 1 , wherein the processor is further programmed to generate an error report based on the contouring error.

9. The system of claim 8 , wherein the processor is further programmed to transmit the error report over a computer network.

10. A system for validating accuracy of delineated contours in computerized imaging, comprising:
a storage unit including one or more approved radiation therapy contours and a patient specific radiation therapy contour; and
a processor programmed to:
receive the one or more approved radiation therapy contours,
calculate at least one attribute of the one or more approved radiation therapy contours,
construct assessment criterion parameters using machine learning,
receive the patient specific radiation therapy contour from the storage unit,
calculate at least one patient specific radiation therapy contour attribute using the patient specific radiation therapy contour, and
detect contouring error by fitting the at least one patient specific radiation therapy contour to the assessment criterion parameters.

Assignees

• Univ Washington

Inventors

• Chen Hsin-Chen
• Mutic Sasa
• Tan Jun
• Altman Michael
• Kavanaugh James
• Li Hua

Classifications

• A61N5/1039 Primary

  using functional images, e.g. PET or MRI · CPC title

• G06T2207/30004

  Biomedical image processing · CPC title

• G06T7/13 Primary

  Edge detection · CPC title

• G06T2207/10116

  X-ray image · CPC title

• G06T2207/10081

  Computed x-ray tomography [CT] · CPC title