Soap bar having enhanced antibacterial activity

Patent metadata

Field	Value
Publication number	US-10370622-B2
Application number	US-201414784197-A
Country	US
Kind code	B2
Filing date	Apr 9, 2014
Priority date	Apr 16, 2013
Publication date	Aug 6, 2019
Grant date	Aug 6, 2019

Abstract

A soap bar comprising: (a) 25 to 85% by weight, based on the total weight of the bar, of fatty acid soap; (b) 0.1 to 100 ppm by weight, based on the total weight of the bar, of at least one silver (I) compound having a selected silver ion solubility, wherein at 25° C., a 1 wt % solution of the bar in water has a pH of from 9 to 11.

First claim

The invention claimed is:

1. A soap bar comprising:
(a) 25 to 85% by weight, based on the total weight of the bar, of fatty acid soap;
(b) 0.1 to 100 ppm by weight, based on the total weight of the bar, of at least one silver (I) compound having a silver ion solubility in water at 25° C. of at least 1×10 −4 mol/L,
wherein at 25° C., a 1 wt % solution of the bar in water has a pH in a range of from 9 to 11.

2. The bar according to claim 1 wherein component (b) is one or more silver compounds selected from one group consisting of silver oxide, silver nitrate, silver acetate, silver sulfate, silver benzoate, silver salicylate, silver carbonate, silver citrate and silver phosphate.

3. The bar according to claim 1 wherein the silver (I) compound comprises silver oxide.

4. The bar according to claim 1 wherein the fatty acid soap comprises an alkali metal salt of aliphatic alkane- and/or alkene monocarboxylic acids having 8 to 18 carbon atoms.

5. The bar according to claim 1 wherein component (b) is one or more silver compounds selected from one group consisting of silver oxide, silver sulfate and silver citrate.

6. The bar according to claim 1 wherein component (b) is present in an amount of 1 to 50 ppm by weight, based on the total weight of the bar.

7. The bar according to claim 1 wherein component (b) is present in an amount of 5 to 20 ppm by weight, based on the total weight of the bar.

8. The bar according to claim 1 wherein the fatty acid soap (a) has been neutralized to an excess free alkali level of 0.01 to 0.05 wt %.

9. A method of reducing Gram positive bacteria on human skin, which comprises;
(i) lathering a high pH solid soap composition to form an aqueous soap dilution containing the high pH solid soap composition at a level of from 1 to 25% by weight, based on the total weight of the dilution,
wherein the high pH solid soap composition comprises:
(a) 25 to 85% by weight, based on the total weight of the high pH solid soap composition, of fatty acid soap; and
(b) 0.1 to 100 ppm by weight, based on the total weight of the high pH solid soap composition, of at least one silver(I) compound having a silver ion solubility in water at 25° C. of at least 1×10 4 mol/L,

wherein a 1% solution of said high pH solid soap composition has a pH of from 9 to 11;

(ii) applying the aqueous soap dilution to the skin for a contact time of less than 1 minute; and
(iii) rinsing the aqueous soap dilution from the skin;
wherein the method provides a log 10 reduction in biocidal activity against Gram positive bacteria.

10. The method according to claim 9 wherein the aqueous soap dilution is applied to the skin for a contact time of not more than 30 seconds.

11. The method of claim 10 wherein the high pH solid soap composition comprises from 1 to 50 ppm by weight of the silver (I) compound.

12. The method according to claim 9 wherein a 1 wt. % solution of the high pH solid soap composition in water has a pH of from 9.5 to 10.8.

13. The method of claim 10 , wherein the contact time period is from 10 to 30 seconds.

14. The method according to claim 9 , wherein the high pH solid soap composition provides a log 10 reduction in biocidal activity against Staphylococcus aureus ATCC 6538 of at least 2 at a contact time of 10 seconds.

15. The method according to claim 9 , wherein the high pH solid soap composition provides a log 10 reduction in biocidal activity against Staphylococcus aureus ATCC 6538 of at least 3 at a contact time of 10 seconds.

16. The method according to claim 9 , wherein the silver (I) compound is selected from the group consisting of silver oxide, silver nitrate, silver acetate, silver sulfate, silver benzoate, silver salicylate, silver carbonate, silver citrate and silver phosphate.

17. A soap bar comprising:
(a) 25 to 85% by weight, based on the total weight of the bar, of fatty acid soap;
(b) 0.1 to 100 ppm by weight, based on the total weight of the bar, of at least one silver (I) compound having a silver ion solubility in water at 25° C. of at least 1×10′ mol/L,
wherein:
a 1 wt % solution of the bar in water at 25° C. has a pH in a range of from 9 to 11; and
the silver (I) compound is selected from the group consisting of silver oxide, silver nitrate, silver acetate, silver sulfate, silver carbonate, silver citrate and silver phosphate.

18. The bar according to claim 17 , wherein the fatty acid soap comprises an alkali metal salt of aliphatic alkane- and/or alkene monocarboxylic acids having 8 to 18 carbon atoms.

19. The bar according to claim 17 , wherein the fatty acid soap (a) has been neutralized to an excess free alkali level of 0.01 to 0.05 wt %.

Assignees

• Conopco Inc

Inventors

• Chandar Prem
• Wu Guohui
• Kumar Nitish
• Manthena Vamsi Krishna
• Nayak Kalpana Kamalakar
• Sanzgiri Vibhav Ramrao
• Shiloach Anat

Classifications

• C11D9/26

  containing oxygen {(C11D9/225 takes precedence)} · CPC title

• C11D9/12

  Carbonates · CPC title

• C11D9/10 Primary

  Salts · CPC title

• C11D9/08

  Water-soluble compounds · CPC title

• C11D9/00

  Compositions of detergents based essentially on soap (compositions containing resin soap C11D15/04) · CPC title