Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
US-9439941-B2 · Sep 13, 2016 · US
US10369237B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10369237-B2 |
| Application number | US-201515122749-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 10, 2015 |
| Priority date | Mar 10, 2014 |
| Publication date | Aug 6, 2019 |
| Grant date | Aug 6, 2019 |
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Methods and devices for sterilizing viscous peptide compositions which have shear thinning rheological properties at high concentrations.
Opening claim text (preview).
What is claimed is: 1. A method for sterilizing a liquid peptide composition whose sequence comprises a series of repeating units of IEIK as set forth in SEQ ID NO:6 comprising subjecting the liquid peptide composition to autoclave treatment. 2. The method of claim 1 , wherein the method does not involve sterilizing filtration. 3. A method for sterilizing a liquid peptide composition whose sequence comprises a series of repeating units of IEIK as set forth in SEQ ID NO:6 comprising subjecting the liquid peptide composition to heat treatment performed at about 121° C. for about 25 minutes. 4. The method of claim 1 , wherein the liquid peptide composition has a concentration within the range of about 0.01% to about 10%. 5. The method of claim 1 , wherein the liquid peptide composition comprises IEIK13 as set forth in SEQ ID NO: 3. 6. The method of claim 1 , wherein the method does not degrade the liquid peptide composition. 7. The method of claim 3 , wherein the liquid peptide composition has a concentration within the range of about 0.01% to about 10%. 8. The method of claim 3 , wherein the liquid peptide composition comprises IEIK13 as set forth in SEQ ID NO: 3. 9. The method of claim 3 , wherein the method does not degrade the liquid peptide composition.
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