Replacement mitral valves

Patent metadata

Field	Value
Publication number	US-10368990-B2
Application number	US-201816012666-A
Country	US
Kind code	B2
Filing date	Jun 19, 2018
Priority date	Jan 23, 2017
Publication date	Aug 6, 2019
Grant date	Aug 6, 2019

Abstract

A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.

First claim

The invention claimed is:

1. A prosthetic mitral valve comprising:
a valve support assembly comprising a ventricular anchor, a central portion, and an atrial anchor, wherein the valve support assembly comprises a plurality of diamond-shaped cells, the valve support assembly configured to self-expand from a collapsed configuration to an expanded configuration;
a plurality of leaflets secured to the valve support assembly; and
a plurality of retention hooks attached to the ventricular anchor, each of the retention hooks extending from an apex of an interior diamond-shaped cell, wherein each of the retention hooks curves radially outwards to point in an atrial direction when the valve support assembly is in the expanded configuration, each retention hook having a ratio of radius of curvature to thickness of 4:1 or greater.

2. The prosthetic mitral valve of claim 1 , wherein the ratio is between 4:1 and 8:1.

3. The prosthetic mitral valve of claim 1 , wherein each of the plurality of retention hooks is configured to point at an angle of 10-40 degrees relative to a central longitudinal axis of the prosthetic mitral valve.

4. The prosthetic mitral valve of claim 3 , wherein the angle is approximately 28°.

5. The prosthetic mitral valve of claim 1 , wherein a radius of curvature of each of the plurality of retention hooks is less than 4 mm.

6. The prosthetic mitral valve of claim 1 , wherein a radius of curvature of each of the plurality of retention hooks is between 2 mm-4 mm.

7. The prosthetic mitral valve of claim 1 , wherein a thickness of each of the plurality of retention hooks is less than 1.6 mm.

8. The prosthetic mitral valve of claim 1 , wherein a thickness of each retention hooks is between 0.25 mm and 1 mm.

9. The prosthetic mitral valve of claim 1 , wherein a ratio of width to thickness of each retention hook is between 0.3:1 and 1:1.

10. The prosthetic mitral valve of claim 1 , wherein each hook is configured to engage approximately 3-10 mm of mitral valve tissue when the valve support assembly is in the expanded configuration.

11. The prosthetic mitral valve of claim 1 , wherein the plurality of retention hooks are integral with the valve support assembly.

12. The prosthetic mitral valve of claim 1 , wherein the valve support assembly includes an anchor assembly comprising the ventricular and atrial anchors and the central portion and an annular strut frame positioned radially within the anchor assembly.

13. The prosthetic mitral valve of claim 12 , wherein the plurality of retention hooks are attached to the anchor assembly.

14. The prosthetic mitral valve of claim 1 , wherein the central portion is configured to align with a native valve orifice, and wherein the ventricular anchor and the atrial anchors are configured to compress native cardiac tissue therebetween.

15. The prosthetic mitral valve of claim 1 , wherein a retention hook extends from each apex in a circumferential line around the prosthetic mitral valve except a position closest to a leaflet attachment point.

16. A prosthetic mitral valve comprising:
a valve support assembly comprising a ventricular anchor, a central portion, and an atrial anchor, the valve support assembly configured to self-expand from a collapsed configuration to an expanded configuration;
a plurality of leaflets secured to the valve support assembly; and
a plurality of retention hooks attached to the ventricular anchor, wherein each of the retention hooks curves radially outwards to point in an atrial direction when the valve support assembly is in the expanded configuration, each retention hook having a ratio of radius of curvature to thickness of greater than 4:1 and points at an angle of approximately 28° relative to a central longitudinal axis of the prosthetic mitral valve.

17. The prosthetic mitral valve of claim 16 , wherein a ratio of width to thickness of each retention hook is between 0.3:1 and 1:1.

18. The prosthetic mitral valve of claim 16 , wherein each hook is configured to engage approximately 3-10 mm of mitral valve tissue when the valve support assembly is in the expanded configuration.

19. The prosthetic mitral valve of claim 16 , wherein a radius of curvature of each of the plurality of retention hooks is less than 4 mm.

Assignees

• Cephea Valve Tech Inc

Inventors

• Noe Spencer
• Wallace Dan
• Oakden Jonathan

Classifications

• A61F2/2418 Primary

  Scaffolds therefor, e.g. support stents · CPC title

• A61F2230/0054

  V-shaped · CPC title

• A61F2230/001

  Figure-8-shaped, e.g. hourglass-shaped · CPC title

• A61F2220/0016

  with sharp anchoring protrusions, e.g. barbs, pins, spikes · CPC title

• A61F2220/0075

  sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable · CPC title