Sphingosine kinase type 1 inhibitors and uses thereof
US-9974758-B2 · May 22, 2018 · US
Methods and intermediates for synthesizing SK1-I
US10364211B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-10364211-B1 |
| Application number | US-201816169056-A |
| Country | US |
| Kind code | B1 |
| Filing date | Oct 24, 2018 |
| Priority date | Oct 25, 2017 |
| Publication date | Jul 30, 2019 |
| Grant date | Jul 30, 2019 |
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- Title
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Abstract
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The invention provides methods for synthesizing the compound (2R,3S,4E)-N-methyl-5-(4′-pentylphenyl)-2-aminopent-4-ene-1,3-diol, also known as SK1-I, and intermediate compounds used in its synthesis.
First claim
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What is claimed is: 1. A method for synthesizing the compound comprising the reaction steps of: (vii) reacting with DIBAL in the presence of Rochelle salt, thereby obtaining
Assignees
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Classifications
- C07D263/06Primary
with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms · CPC title
- C07C215/28Primary
and containing six-membered aromatic rings · CPC title
from amines with formation of carbamate groups · CPC title
Optical isomers · CPC title
by reactions not involving the formation of carbamate groups · CPC title
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Frequently asked questions
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- What does patent US10364211B1 cover?
- The invention provides methods for synthesizing the compound (2R,3S,4E)-N-methyl-5-(4′-pentylphenyl)-2-aminopent-4-ene-1,3-diol, also known as SK1-I, and intermediate compounds used in its synthesis.
- Who is the assignee on this patent?
- Enzo Biochem Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D263/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 30 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).