Imaging flow cytometer using spatial-temporal transformation
US-2024094129-A1 · Mar 21, 2024 · US
US10362245B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10362245-B2 |
| Application number | US-201816149642-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 2, 2018 |
| Priority date | Feb 1, 2013 |
| Publication date | Jul 23, 2019 |
| Grant date | Jul 23, 2019 |
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An image acquisition system 1 includes: a light source 3 which outputs illumination light; an optical scanner 7 which scans a sample S with the illumination light; an optical scanner control unit 9; a detection optical system 15, 17 which focuses fluorescence from the sample S; an imaging device 19 which has a light receiving surface 19c in which a plurality of pixel rows 19d are arranged, and an imaging control section 19b, and which can perform signal readout of each of the plurality of pixel rows 19d from the light receiving surface 19c; and a calculation unit 21 which calculates an interval of signal readout between adjacent pixel rows 19d, based on a moving speed of an illuminated region on the light receiving surface 19c; the imaging control section 19b controls signal readout of each pixel row 19d, based on the interval of the signal readout thus calculated.
Opening claim text (preview).
The invention claimed is: 1. An imaging apparatus for performing signal readout by rolling readout of each of a plurality of pixel rows to acquire an image of an object illuminated by a scanned illumination light, comprising: a light receiving section in which the plurality of pixel rows are arranged; an imaging control section for controlling signal readout of the light receiving section based on a driving clock; and an external signal receiving section coupled to the imaging control section and for receiving an external signal, wherein the external signal receiving section is coupled to a calculation unit which generates the external signal, wherein the external signal comprises data indicative of an interval of start timing of signal readout between adjacent pixel rows, wherein the interval of start timing of signal readout between adjacent pixel rows is calculated by the calculation unit to synchronize with a scanning of the object with the illumination light, and wherein start timing of signal readout of each pixel row is controlled based on the external signal. 2. The imaging apparatus according to claim 1 , wherein the interval of start timing of signal readout between adjacent pixel rows includes a period of the signal readout. 3. The imaging apparatus according to claim 2 , wherein the period of the signal readout is variable. 4. The imaging apparatus according to claim 3 , wherein the interval of start timing of signal readout between adjacent pixel rows is adjusted by changing the number of cycles in the driving clock which defines the period of the signal readout. 5. An image acquisition system comprising the imaging apparatus of claim 1 and the calculation unit. 6. The image acquisition system according to claim 5 , wherein the calculation unit is configured to be input with the moving speed of the illumination light on the light receiving section. 7. The image acquisition system according to claim 5 , wherein the image acquisition system comprises a light scanning unit for scanning the object with the illumination light and an optical system for guiding light from the object; and wherein the calculation unit is configured to acquire information about speed of scanning the object with the illumination light from the light scanning unit. 8. A calculation unit coupled to the imaging apparatus of claim 1 and configured to send the external signal. 9. The calculation unit according to claim 8 , wherein the calculation unit is configured to be input with the moving speed of the illumination light on the light receiving section. 10. The calculation unit according to claim 8 , wherein the object is scanned by a light scanning unit with the illumination light; and wherein the calculation unit is configured to acquire information about speed of scanning the object with the illumination light from the light scanning unit.
by influencing the scene brightness using illuminating means · CPC title
by controlling rolling shutters in CMOS SSIS · CPC title
Scanning microscopes (scanning near field optical microscopes G01Q60/18) · CPC title
Control of cameras or camera modules · CPC title
Addressed sensors, e.g. MOS or CMOS sensors · CPC title
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