Airy beam light sheet and airy beam light sheet microscope

Patent metadata

Field	Value
Publication number	US-10353188-B2
Application number	US-201515326073-A
Country	US
Kind code	B2
Filing date	Jul 29, 2015
Priority date	Jul 30, 2014
Publication date	Jul 16, 2019
Grant date	Jul 16, 2019

Abstract

An optical system for generating an Airy beam light sheet comprising an optical arrangement for generating a Gaussian beam, and an optical element for converting the Gaussian beam into an Airy beam light sheet, wherein a single optical element is provided for converting the Gaussian beam into an Airy beam light sheet.

First claim

The invention claimed is:

1. An optical system for generating a modulated Airy beam or a modulated Airy beam light sheet, said system comprising an optical arrangement for generating a Gaussian beam, and a modulation arrangement configured to impart, on the Gaussian beam, a cubic phase modulation and a further modulation in phase and/or amplitude, which further modulation is additional to the cubic phase modulation, to thereby convert the Gaussian beam into a modulated Airy beam or a modulated Airy beam light sheet having an arbitrary intensity profile along a direction of propagation,
wherein the further modulation in phase and/or amplitude is selected so as to provide the modulated Airy beam or the modulated Airy beam light sheet with a peak intensity that increases with propagation of the modulated Airy beam or the modulated Airy beam light sheet, or
wherein the further modulation in phase and/or amplitude is selected so as to at least partially compensate for attenuation or scattering losses experienced by the peak intensity of the modulated Airy beam or the modulated Airy beam light sheet during propagation of the modulated Airy beam or the modulated Airy beam light sheet in a lossy medium.

2. An optical system as claimed in claim 1 wherein the modulation arrangement comprises an optical element which is configured to impart the cubic phase modulation on the Gaussian beam thereby to convert the Gaussian beam to an Airy beam or an Airy beam light sheet, wherein the optical element is a unitary optical element.

3. An optical system as claimed in claim 2 wherein the optical element comprises a cylindrical lens that is tilted relative to a direction of propagation of the Gaussian beam.

4. An optical system as claimed in claim 2 comprising a first collimator for collimating the Gaussian beam prior to incidence on the optical element.

5. An optical system as claimed in claim 4 comprising a second collimator for collimating the Gaussian beam after incidence on the optical element.

6. An optical system as claimed in claim 2 comprising a variable aperture/slit for varying the size of the beam incident on the optical element.

7. An optical system as claimed in claim 1 wherein the optical system is a light sheet optical microscope.

8. An optical system as claimed in claim 2 wherein the modulation arrangement comprises a modulation device or element imparting the additional modulation in phase and/or amplitude of the Airy beam light sheet to provide a desired intensity modulation.

9. An optical system as claimed in claim 8 wherein the modulation device or element is positioned before the optical element.

10. An optical system as claimed in claim 1 wherein the modulation arrangement is static or variable.

11. An optical system as claimed in claim 10 wherein the modulation arrangement comprises a diffractive optical element and/or the modulation arrangement comprises a digital micromirror device and/or a spatial light modulator.

12. An optical system as claimed in claim 1 , wherein the modulation arrangement is adapted to multiply an Airy beam spatial spectral function by a spatial spectral modulation function, thereby to produce the modulated Airy beam or the modulated Airy beam light sheet, wherein the Airy beam spatial spectral function is associated with the cubic phase modulation, and the spatial spectral modulation function is associated with the further modulation in phase and/or amplitude.

13. An optical system as claimed in claim 2 wherein the optical element is a static/passive diffractive optical element.

Assignees

• Univ Court Univ St Andrews

Inventors

• Mazilu Michael
• Vettenburg Tom
• Dholakia Kishan
• Preciado Miguel
• Yang Zhengyi

Classifications

• G02B26/06

  for controlling the phase of light (G02B26/08 takes precedence {, measuring optical phase difference G01J9/00}) · CPC title

• G02B27/0966

  Cylindrical lenses (cylindrical lenses per se G02B3/06) · CPC title

• G02B21/06 Primary

  Means for illuminating specimens · CPC title

• G02B27/0927

  Systems for changing the beam intensity distribution, e.g. Gaussian to top-hat · CPC title

• G02B26/02

  for controlling the intensity of light {(G02B26/004 takes precedence)} · CPC title