Tuned synthetic dendrimer calibrants for mass spectrometry

US10347476B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10347476-B2
Application numberUS-201314402474-A
CountryUS
Kind codeB2
Filing dateMay 21, 2013
Priority dateMay 21, 2012
Publication dateJul 9, 2019
Grant dateJul 9, 2019

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

Provided are synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to batch synthesis as mixtures. The latter characteristic enables parallel preparation of higher molecular weight compounds displaying useful distributions of discrete molecular weights, thereby providing multi-point mass spectrometry calibration standards. Methods of making, tuning and using said calibrants are provided.

First claim

Opening claim text (preview).

What is claimed is: 1. A composition comprising: a first dendrimer comprising a first core molecule, wherein said first core molecule is selected from the group consisting of: a molecule comprising between 1 and 8 alcohol functionalities, a molecule comprising between 1 and 8 amine functionalities, and a molecule comprising at least one amine functionality and at least one alcohol functionality; wherein the combined number of amine and alcohol functionalities of said first core molecule is at least 2 but no greater than 8; and wherein said first core molecule comprises three iodine atoms; and a second dendrimer comprising a second core molecule, wherein said second core molecule comprises a subsequent generation dendrimer of said first core molecule. 2. The composition of claim 1 wherein said first core molecule comprises 2,4,6-triiodolphenol.

Assignees

Inventors

Classifications

  • Dendritic macromolecules · CPC title

  • C07D319/06Primary

    not condensed with other rings · CPC title

  • in which the condensed system contains four or more hetero rings · CPC title

  • Mass spectrometers {(mass spectrometers per se H01J49/00)} · CPC title

  • Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10347476B2 cover?
Provided are synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to batch synthesis as mixtures. The latter characteristic enables parallel preparation of higher molecular weight compounds displaying useful distributions of discrete molecular…
Who is the assignee on this patent?
The Administrators Of The Tulane Educational Fund
What technology area does this patent fall under?
Primary CPC classification C07D319/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jul 09 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).