Method and apparatus for sample injection in liquid chromatography
US-9618128-B2 · Apr 11, 2017 · US
US10344877B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10344877-B2 |
| Application number | US-201615365781-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 30, 2016 |
| Priority date | Dec 1, 2015 |
| Publication date | Jul 9, 2019 |
| Grant date | Jul 9, 2019 |
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A multi-port, multi-mode valve includes: a valve housing; multiple ports on the valve housing, a spacing between first and second ports being smaller than a spacing between third and fourth ports; and a stemshell positioned at least partly inside the valve housing, the stemshell having at least two channels configured for selectively coupling one or more of the ports to a selected at least other one of the ports.
Opening claim text (preview).
What is claimed is: 1. A multi-port, multi-mode valve comprising: a valve housing; at least a first port, a second port, a third port, a fourth port, and a fifth port on the valve housing; and a stemshell positioned at least partly inside the valve housing, the stemshell including a first channel and a second channel configured for selectively coupling either the first port or the second port to the third port while the fourth port remains continuously coupled to the fifth port, each of the first channel and the second channel having a first end and a second end, wherein the stemshell is a single and unitary actuated component of the multi-port, multi-mode valve and each side of the first channel and each side of the second channel are formed by the stemshell such that any fluid flow between coupled ports of the valve housing occurs internal to the stemshell via the first channel and the second channel. 2. The multi-port, multi-mode valve of claim 1 , wherein a spacing between the first port and the second port is smaller than a spacing between the third port and the fourth port. 3. The multi-port, multi-mode valve of claim 1 , wherein the first port, the second port, the third port, the fourth port and the fifth port are oriented within a common plane. 4. The multi-port, multi-mode valve of claim 1 , wherein some of the ports are oriented within a common plane, and wherein at least the second port has a different orientation than the common plane. 5. The multi-port, multi-mode valve of claim 4 , wherein the second port is aligned with an axis of rotation for the stemshell. 6. The multi-port, multi-mode valve of claim 1 , wherein the stemshell is configured for rotating between positions that correspond to different couplings between the ports. 7. The multi-port, multi-mode valve of claim 1 , wherein the stemshell is cylindrical. 8. The multi-port, multi-mode valve of claim 1 , wherein the first channel has a first arcuate shape and the second channel has a second arcuate shape. 9. The multi-port, multi-mode valve of claim 8 , wherein the first arcuate shape and the second arcuate shape face in opposite directions. 10. The multi-port, multi-mode valve of claim 8 , wherein the stemshell is configured so that the first end of the first channel couples to either the first port or the second port, and so that the second end of the first channel couples to the fifth port, and wherein the first channel is configured so that the second end thereof couples to the fifth port both when the first end of the first channel couples to the first port and when the first end of the first channel couples to the second port. 11. The multi-port, multi-mode valve of claim 10 , wherein the stemshell is configured so that the first end of the second channel couples to the third port, and wherein the second channel is configured so that the first end thereof couples to the third port both when the first end of the first channel couples to the first port and when the first end of the first channel couples to the second port. 12. The multi-port, multi-mode valve of claim 11 , wherein the second channel is configured so that the second end thereof couples to the fourth port both when the first end of the first channel couples to the first port and when the first end of the first channel couples to the second port. 13. The multi-port, multi-mode valve of claim 1 , wherein the first port corresponds to a component conduit and wherein the second port corresponds to a component bypass conduit. 14. The multi-port, multi-mode valve of claim 1 , wherein a width of the first port at the stemshell is narrower than the widths of the third port and the fourth port at the stemshell. 15. The multi-port, multi-mode valve of claim 14 , wherein a width of the second port at the stemshell is narrower than widths of the third port and the fourth port at the stemshell. 16. The multi-port, multi-mode valve of claim 1 , wherein the stemshell is configured for selectively coupling either the first port or the second port to the third port while the fourth port remains continuously coupled to the fifth port during a parallel operation mode. 17. The multi-port, multi-mode valve of claim 1 , wherein the stemshell is configured for selectively coupling either the first port or the second port to the third port while the fourth port remains continuously coupled to the fifth port during a serial operation mode. 18. A method performed with regard to a multi-port, multi-mode valve having at least a first port, a second port, a third port, a fourth port, and a fifth port, the method comprising: orienting, in the multi-port, multi-mode valve, a stemshell thereof so that a first channel of the stemshell couples the first port to the third port, and so that a second channel of the stemshell couples the fourth port to the fifth port, each of the first channel and the second channel having a first end and a second end, wherein the stemshell does not couple the second port to any of the other ports; receiving a signal corresponding to an instruction to instead couple the second port to the third port; and in response to the signal, orienting the stemshell so that the first channel of the stemshell couples the second port to the third port, while the second channel of the stemshell continuously couples the fourth port to the fifth port, wherein the stemshell does not couple the first port to any of the other ports, and wherein the stemshell is a single and unitary component of the multi-port, multi-mode valve and each side of the first channel and each side of the second channel are formed by the stemshell such that any fluid flow between coupled ports of the multi-port, multi-port valve occurs internal to the stemshell via the first channel and the second channel.
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