Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
US-10167489-B2 · Jan 1, 2019 · US
Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
US10344305B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10344305-B2 |
| Application number | US-201816186316-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 9, 2018 |
| Priority date | Nov 3, 2010 |
| Publication date | Jul 9, 2019 |
| Grant date | Jul 9, 2019 |
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- Title
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Abstract
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Methods and compositions for the production of dielectric fluids from lipids produced by microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a lipid pathway modification enzyme, a fatty acyl-ACP thioesterase, a desaturase, a fatty acyl-CoA/aldehyde reductase, and/or an acyl carrier protein are useful in manufacturing dielectric fluids.
First claim
Opening claim text (preview).
What is claimed is: 1. A recombinant Chlorella or Prototheca cell engineered to ablate or downregulate expression of an endogenous fatty acyl-ACP thioesterase gene. 2. The cell of claim 1 , wherein the endogenous fatty acyl-ACP thioesterase gene is downregulated by an inhibitory RNA. 3. The cell of claim 1 , wherein the Prototheca or Chlorella cell is of the species Prototheca moriformis or Chlorella protothecoides. 4. The cell of claim 1 , wherein the Chlorella or Prototheca cell further comprises one or more exogenous genes that encode a sucrose invertase, a fatty acyl-ACP thioesterase, a desaturase, or an inhibitory RNA that targets an endogenous desaturase. 5. The cell of claim 4 , wherein the one or more expressed exogenous genes encode(s) an inhibitory RNA that targets an endogenous desaturase. 6. The cell of claim 4 , wherein the one or more exogenous genes encode(s) sucrose invertase, fatty acyl-ACP thioesterase or desaturase. 7. The Cell of claim 6 , wherein the Prototheca or Chlorella is of the species Prototheca moriformis or Chlorella protothecoides.
Assignees
Inventors
Classifications
by filtration, e.g. including ultra filtration, dialysis (C11B3/005 takes precedence) · CPC title
characterised by the production or working-up · CPC title
Vectors or expression systems specially adapted for eukaryotic hosts · CPC title
by a combination of two or more of the means hereafter · CPC title
Oleoyl-[acyl-carrier-protein] hydrolase (3.1.2.14), i.e. ACP-thioesterase · CPC title
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- What does patent US10344305B2 cover?
- Methods and compositions for the production of dielectric fluids from lipids produced by microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a lipid pathway modi…
- Who is the assignee on this patent?
- Corbion Biotech Inc
- What technology area does this patent fall under?
- Primary CPC classification C11B1/025. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 09 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).