Ehrlichial invasin for immunization, diagnosis, and cell delivery
US-2015313983-A1 · Nov 5, 2015 · US
US10335476B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10335476-B2 |
| Application number | US-201514919494-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 21, 2015 |
| Priority date | Oct 21, 2014 |
| Publication date | Jul 2, 2019 |
| Grant date | Jul 2, 2019 |
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Official abstract text for this publication.
Certain embodiments are direct to a vaccine composition comprising an immunizing amount of an Ehrlichia sonicate, wherein the Ehrlichia sonicate elicits a protective physiologic response. In certain aspects the Ehrlichia is one or more of E. canis, E. chaffeensis, E. muris, E. ruminantium, E. ewingii , and E. ovis.
Opening claim text (preview).
The invention claimed is: 1. A vaccine composition comprising an immunizing amount of an Ehrlichia muris sonicate, wherein the Ehrlichia muris sonicate elicits an antibody independent protective immune response within 7 days of Ehrlichia muris challenge. 2. The vaccine composition of claim 1 , further comprising an adjuvant.
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