Apparatus for determining a property of an object using ultrasound scatter

Patent metadata

Field	Value
Publication number	US-10335192-B2
Application number	US-201113643116-A
Country	US
Kind code	B2
Filing date	Apr 15, 2011
Priority date	Apr 28, 2010
Publication date	Jul 2, 2019
Grant date	Jul 2, 2019

Abstract

A monitoring apparatus for monitoring an ablation procedure applied to an object comprises an ultrasound signal providing unit for providing an ultrasound signal. The ultrasound signal is produced by sending ultrasound pulses out to the object, by subsequently receiving dynamic echo series after the ultrasound pulses have been reflected by the object, and finally by generating the ultrasound signal depending on the received dynamic echo series, whereby ultrasound scattering properties of the object are determined that represent blood perfusion. The monitoring apparatus further comprises an ablation depth determination unit for determining an ablation depth from the provided ultrasound signal.

First claim

The invention claimed is:

1. Property determining apparatus for determining a property of an object, wherein the property determining apparatus comprises:
an ultrasound signal providing unit ( 18 ) for providing an ultrasound signal produced by
sending an ultrasound pulse out to the object,
receiving echo series from the object, and
generating the ultrasound signal depending on the received echo series,

a scatter determination unit ( 8 ) for determining at least one scatter value being indicative of a scatter of the ultrasound pulse by a fluid perfusing the object, wherein the scatter determination unit ( 8 ) is adapted to determine the at least one scatter value based on a histogram of ultrasound intensities of the ultrasound signal,
a property determination unit ( 15 ) for determining a property of the object depending on the at least one scatter value.

2. The property determining apparatus as defined in claim 1 , wherein the object ( 3 ) is a biological object comprising tissue and wherein the property determination unit ( 15 ) is adapted to determine whether a part of the tissue comprises ablated tissue or non-ablated tissue based on the at least one scatter value as the property of the object.

3. The property determining apparatus as defined in claim 1 , wherein the provided ultrasound signal represents the scattering by the fluid at at least one of a) different depths within the object and b) different times, wherein the ultrasound signal is sampled by sample windows corresponding to the at least one of a) different depths and b) different times, wherein the scatter value determination unit ( 8 ) is adapted to determine the at least one scatter value for each one of the sample windows, wherein for each respective one of the sample windows, the at least one scatter value is determined based on a part of the ultrasound signal which corresponds to the respective sample window and wherein the property determination unit is adapted to determine the property for the respective sample window based on the at least one scatter value determined for the respective sample window.

4. The property determining apparatus as defined in claim 3 , wherein each of the sample windows corresponds to several ultrasound intensities of the ultrasound signal and wherein the scatter determination unit is adapted to determine the at least one scatter value for each sample window, wherein the histogram comprises the ultrasound intensities within the respective sample window.

5. The property determining apparatus as defined in claim 4 , wherein the histogram is at least one of a first-order histogram and a second-order histogram.

6. The property determining apparatus as defined in claim 5 , wherein the scatter value is at least one of: a first-order mean of the first-order histogram, a first-order variance of the first-order histogram, a first-order entropy of the first-order histogram, a second-order entropy of the second-order histogram, a second-order energy of the second-order histogram, a second-order homogeneity of the second-order histogram, a second-order contrast of the second-order histogram, a second-order cluster tendency of the second-order histogram, a second-order shape of the second-order histogram, a second-order correlation of the second-order histogram and a second-order correlation derivative of the second-order histogram.

7. The property determining apparatus as defined in claim 3 , wherein the property determination unit is further adapted to apply a duster analysis to the sample windows, wherein the sample windows are clustered depending on the at least one scatter value determined for each respective sample window, and the property determination unit is further adapted to assign the property to each of the clusters of sample windows.

8. The property determining apparatus as defined in claim 1 , wherein the ultrasound signal providing unit ( 18 ) is adapted to provide the ultrasound pulses at a frequency being larger than 10 MHz.

9. The property determining apparatus as defined in claim 1 , wherein the ultrasound signal providing unit ( 18 ) is an ultrasound transducer integrated into a catheter or a needle.

10. The property determining apparatus as defined in claim 1 , wherein said at least one scatter value is determined independently of heating the object.

11. An object influencing apparatus for influencing an object, the object influencing apparatus comprising an object influencing unit ( 4 , 23 , 24 ) for influencing the object, the property determining apparatus as defined in claim 1 , and a control unit adapted for controlling the object influencing apparatus depending on the property determined by the property determination apparatus.

12. A property determining method for determining a property of an object, wherein the property determining method comprises:
providing by an ultrasound transducer, an ultrasound signal produced by
sending an ultrasound pulse out to the object,
receiving echo series from the object, and
generating the ultrasound signal depending on the received echo series,

determining, in a processor executing a program code means, at least one scatter value being indicative of a scatter of the ultrasound pulse by a fluid perfusing the object, wherein the at least one scatter value is based on a histogram of ultrasound intensities of the ultrasound signal,
determining, in a processor executing a program code means, a property of the object depending on the at least one scatter value.

13. The method of claim 12 , further comprising the step of influencing the object based on the determined property.

Assignees

• Harks Godefridus Antonius
• Zuo Fei
• Deladi Szabolcs
• Fokkenrood Steven Antonie Willem
• Mihajlovic Nenad
• Koninklijke Philips Nv

Inventors

• Harks Godefridus Antonius
• Zuo Fei
• Deladi Szabolcs
• Fokkenrood Steven Antonie Willem
• Mihajlovic Nenad

Classifications

• A61B2017/00106

  ultrasonic · CPC title

• A61B6/504

  for diagnosis of blood vessels, e.g. by angiography · CPC title

• A61B8/0891

  for diagnosis of blood vessels · CPC title

• A61B2018/00577

  Ablation · CPC title

• A61B2090/3784

  both receiver and transmitter being in the instrument or receiver being also transmitter · CPC title