Pixel array medical devices and methods

Patent metadata

Field	Value
Publication number	US-10335191-B2
Application number	US-201715821325-A
Country	US
Kind code	B2
Filing date	Nov 22, 2017
Priority date	Dec 17, 2010
Publication date	Jul 2, 2019
Grant date	Jul 2, 2019

Abstract

Systems, instruments or devices, and methods or procedures are described in which a scalpet array is applied to a target site with the use of a pattern. The scalpet array comprises scalpets positioned on a device. Skin pixels are incised at the target site via application of a load through the scalpet array. A recipient site is prepared by positioning the pattern at the recipient site and applying the scalpet array to generate skin defects. The incised skin pixels are applied at the skin defects of the recipient site.

First claim

What is claimed is:

1. A method comprising:
positioning a guide plate at a donor site;
aligning a scalpet array of a device with the guide plate at the donor site, wherein the scalpet array comprises at least one scalpet;
incising skin pixels at the donor site with the scalpet array;
preparing a recipient site by positioning the guide plate at the recipient site, and generating with the scalpet array skin defects; and
applying the incised skin pixels at the recipient site.

2. The method of claim 1 , wherein the guide plate comprises perforations arranged in a configuration.

3. The method of claim 2 , wherein the at least one scalpet comprises a plurality of scalpets arranged in the configuration.

4. The method of claim 2 , wherein the scalpet array is arranged according to the configuration.

5. The method of claim 3 , wherein the aligning comprises aligning the scalpet array with at least one set of the perforations.

6. The method of claim 5 , wherein a single scalpet is aligned to incise through the at least one set of the perforations.

7. The method of claim 5 , wherein the at least one scalpet comprises a single scalpet, and the aligning comprises repeatedly applying the scalpet array to the donor site according to an order of the at least one set of the perforations.

8. The method of claim 5 , wherein the incising comprises applying the scalpet array to the donor site directly through the at least one set of the perforations.

9. The method of claim 8 , wherein the incising generates incised skin pixels in the configuration.

10. The method of claim 9 , wherein the incised skin pixels comprise at least one hair follicle.

11. The method of claim 2 , wherein the preparing of the recipient site comprises aligning the scalpet array with the guide plate.

12. The method of claim 11 , wherein the generating of the skin defects comprises applying the scalpet array to the recipient site directly through the at least one set of the perforations.

13. The method of claim 11 , wherein the generating comprises generating the skin defects with a same geometry as the incised skin pixels of a donor site.

14. The method of claim 1 , wherein the incising comprises circumferentially incising skin pixels at the donor site by applying a load via the scalpet array onto subjacent skin surface at the donor site.

15. The method of claim 2 , comprising transecting bases of incised skin pixels extruded through the perforations as a result of the incising.

16. The method of claim 15 , wherein the transecting comprises transecting with a cutting member.

17. The method of claim 16 , comprising configuring the guide plate with a plate frame, and coupling the cutting member to the plate frame.

18. The method of claim 2 , comprising capturing the incised skin pixels on an adherent substrate.

19. The method of claim 18 , comprising aligning the incised skin pixels on the adherent substrate, wherein the incised skin pixels include hair follicles.

20. The method of claim 18 , wherein the incised skin pixels are extruded through the perforations.

21. The method of claim 20 , comprising pulling the adherent substrate away from the donor site and transecting bases of the incised skin pixels during the pulling.

22. The method of claim 18 , wherein the adherent substrate comprises a flexible substrate.

23. The method of claim 18 , wherein the adherent substrate comprises a semi-porous membrane.

24. The method of claim 18 , comprising configuring the guide plate with a plate frame, and coupling the adherent substrate to at least one of the guide plate and the plate frame.

25. The method of claim 24 , comprising coupling the adherent substrate to at least one of the guide plate and the plate frame following the incising.

26. The method of claim 18 , wherein the applying of the incised skin pixels comprises applying the incised skin pixels from the adherent substrate directly to the skin defects at the recipient site.

27. The method of claim 26 , wherein the applying of the incised skin pixels comprises aligning the incised skin pixels with the skin defects at the donor site.

28. The method of claim 27 , wherein the aligning comprises mass aligning of the incised skin pixels according to the configuration.

29. The method of claim 28 , wherein the incised skin pixels include hair follicles.

30. The method of claim 27 , wherein the applying of the incised skin pixels at the recipient site comprises inserting the incised skin pixels into corresponding skin defects at the recipient site.

31. The method of claim 1 , comprising applying a first bandage to the donor site following the incising of the skin pixels, wherein the first bandage closes the donor site and controls a direction that the skin defects of the donor site are closed.

32. The method of claim 1 , comprising applying a second bandage to the recipient site following the applying of the incised skin pixels at the recipient site, wherein the second bandage generates a force at the recipient site.

33. The method of claim 32 , wherein the second bandage comprises an adherent membrane.

34. The method of claim 33 , wherein the second bandage is configured to capture the incised skin pixels at the donor site.

35. The method of claim 33 , wherein the second bandage is configured to stabilize the incised skin pixels inserted at the recipient site.

36. The method of claim 33 , wherein the second bandage is configured to promote neovascularization of the incised skin pixels inserted at the recipient site.

37. The method of claim 33 , wherein the second bandage is configured to promote alignment of the incised skin pixels inserted at the recipient site.

38. The method of claim 1 , comprising providing the device with the scalpet array as a separate component from the guide plate.

39. The method of claim 1 , wherein the positioning of the guide plate comprises applying the guide plate directly to a skin surface at the donor site.

40. The method of claim 1 , wherein a shape of each scalpet of the scalpet array is elliptical.

41. The method of claim 1 , wherein a shape of each scalpet of the scalpet array is circular.

42. The method of claim 1 , wherein a shape of each scalpet of the scalpet array is semicircular.

43. The method of claim 1 , wherein a shape of each scalpet of the scalpet array is one of square, rectangular, and flat.

44. The method of claim 1 , wherein each scalpet of the plurality of scalpets includes a beveled surface.

45. The method of claim 1 , wherein each scalpet of the plurality of scalpets includes at least one pointed surface.

46. The method of claim 1 , wherein each scalpet of the plurality of scalpets includes at least one needle.

47. The method of claim 46 , wherein the at least one needle comprises at least one needle including multiple points.

48. The method of claim 1 , wherein at least one scalpet of the scalpet array comprises a through orifice.

49. The method of claim 1 , wherein the scalpet array is

Assignees

• Srgi Holdings Llc

Inventors

• Knowlton Edward

Classifications

• A61F2/10

  Hair or skin implants · CPC title

• A61B2017/00951

  adhesive · CPC title

• A61B2017/320052

  Guides for cutting instruments · CPC title

• A61B17/32093

  for skin incisions · CPC title

• A61B2017/320064

  with tissue or sample retaining means · CPC title