Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity

Patent metadata

Field	Value
Publication number	US-10334852-B2
Application number	US-201715690914-A
Country	US
Kind code	B2
Filing date	Aug 30, 2017
Priority date	Aug 30, 2016
Publication date	Jul 2, 2019
Grant date	Jul 2, 2019

Abstract

This disclosure relates to pyrido-1,3-oxazine-2,4-diones of Formula I and their use as fungicides.

First claim

What is claimed is:

1. A compound of Formula I,

wherein:
R 1 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1, or multiple R 6 ;
R 2 is hydrogen, C 1 -C 5 alkyl or cycloalkyl, each optionally substituted with 0, 1, or multiple R 6 ;
R 3 is alkyl, cycloalkyl, aryl, or heteroaryl, each optionally substituted with 0, 1, or multiple R 6 ;
R 4 is hydrogen, halo, hydroxyl, alkyl, or alkoxy;
R 5 is alkyl, cycloalkyl, aryl, heteroaryl, alkoxy, aryloxy, heteroaryloxy, thioalkyl, thioaryl, or heterothioaryl, each optionally substituted with 0, 1, or multiple R 6 ;
R 6 is hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkynyl, alkoxy, cyano or heterocyclyl, each optionally substituted with 0, 1, or multiple R 7 ;
R 7 is hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or heterocyclyl; and
R 8 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1, or multiple R 6 .

2. A compound according to claim 1 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl.

3. A compound according to claim 2 , wherein R 2 is C 1 -C 5 alkyl.

4. A compound according to claim 2 , wherein R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 .

5. A compound according to claim 2 , wherein R 4 is hydrogen.

6. A compound according to claim 2 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl, R 2 is C 1 -C 5 alkyl, and R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 , and R 4 is hydrogen.

Assignees

• Dow Agrosciences Llc

Inventors

• Sam Brannon
• Meyer Kevin G
• Yao Chenglin
• Loy Brian A
• Rigoli Jared W
• Babij Nicholas R

Classifications

• A01N43/90 Primary

  having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system · CPC title

• C07D498/04

  Ortho-condensed systems · CPC title

• C07D213/83

  Thioacids; Thioesters; Thioamides; Thioimides · CPC title

• C07D213/81

  Amides; Imides · CPC title

• C07D213/89

  with hetero atoms directly attached to the ring nitrogen atom · CPC title