Cartridge for dispensing a fluid

Patent metadata

Field	Value
Publication number	US-10330693-B2
Application number	US-201615132915-A
Country	US
Kind code	B2
Filing date	Apr 19, 2016
Priority date	May 8, 2012
Publication date	Jun 25, 2019
Grant date	Jun 25, 2019

Abstract

A cartridge for dispensing fluid is presented. The cartridge comprises a valve. The valve comprises a pumping chamber for pumping the fluid. The valve positions a pumping chamber conduit. The pumping chamber conduit is connected to the pumping chamber. The cartridge further comprises a plunger for changing the volume of the pumping chamber. The cartridge further comprises a reservoir conduit for connecting the reservoir with the valve. The valve positions the pumping chamber conduit to connect with the reservoir conduit. The cartridge further comprises an outlet conduit for dispensing the fluid. The valve further rotates the pumping chamber conduit to connect with the outlet conduit.

First claim

We claim:

1. A cartridge for dispensing fluid, the cartridge comprising:
a slide valve, wherein the slide valve comprises a pumping chamber for pumping the fluid, wherein the slide valve positions a pumping chamber conduit and wherein the pumping chamber conduit is connected with the pumping chamber, wherein the slide valve comprises a piston, wherein the pumping chamber is a cavity within the piston;
a plunger for changing the volume of the pumping chamber;
a volume for receiving the piston, wherein the piston is operable for translational motion within the volume for receiving the piston;
a reservoir conduit for connecting a reservoir with the slide valve, wherein the slide valve positions the pumping chamber conduit to connect with the reservoir conduit; and
an outlet conduit for dispensing the fluid, wherein the slide valve translates the pumping chamber conduit to connect with the reservoir conduit and the outlet conduit and wherein the piston is configured for translating the pumping chamber conduit to alternatively connect with the reservoir conduit or the outlet conduit.

2. The cartridge according to claim 1 , further comprises,
a return conduit connected to the reservoir, wherein the pumping chamber conduit receives fluid via the reservoir conduit, wherein the return conduit returns fluid to a second portion of the reservoir, and wherein the slide valve translates the pumping chamber conduit to connect to the return conduit.

3. The cartridge according to claim 1 , further comprises,
a secondary reservoir; and
a secondary reservoir conduit, wherein the slide valve translates the pumping chamber conduit to connect to the secondary reservoir conduit.

4. The cartridge according to claim 3 , further comprises,
a connecting conduit, wherein the connecting conduit transports fluid between the secondary reservoir and the reservoir; and
a membrane blocking the connecting conduit, wherein the membrane is permeable to the fluid.

5. The cartridge according to claim 1 , further comprises,
a coupling assembly for attaching the slide valve and the plunger to an actuator assembly.

6. The cartridge according to claim 1 , wherein the piston and the slide valve are operable for co-linear motion.

7. The cartridge according to claim 1 , wherein the slide valve comprises a reservoir conduit mechanical stop for aligning the pumping chamber conduit with the reservoir conduit, an outlet conduit mechanical stop for aligning the pumping chamber conduit with the outlet conduit or combinations thereof.

8. The cartridge according to claim 1 , wherein the piston comprises two plunger mechanical stops for limiting the motion of the plunger relative to the piston, wherein the plunger actuates the piston.

9. The cartridge according to claim 1 , wherein the piston is configured for translating the pumping chamber conduit relative to the reservoir conduit.

10. The cartridge according to claim 1 , wherein the piston is configured for translating the pumping chamber conduit relative to the outlet conduit.

11. The cartridge according to claim 1 , wherein the slide valve is configured for sealing the outlet conduit when the pumping chamber conduit is translated away from alignment with the outlet conduit.

12. An automatic analyzer for analyzing a biological sample and for holding a cartridge for dispensing fluid, wherein the cartridge comprises a slide valve, wherein the slide valve comprises a pumping chamber for pumping the fluid, wherein the slide valve comprises a piston, wherein the pumping chamber is a cavity within the piston, wherein the slide valve translates a pumping chamber conduit, wherein the pumping chamber conduit is permanently connected with the pumping chamber, wherein the cartridge further comprises a plunger for changing the volume of the pumping chamber, wherein the pumping chamber is formed by the cavity and the plunger, wherein the cartridge further comprises a reservoir conduit for connecting a reservoir with the slide valve, wherein the slide valve translates the pumping chamber conduit to connect with the reservoir conduit, wherein the cartridge further comprises a volume for receiving the piston, wherein the piston is operable for translational motion within the volume for receiving the piston, wherein the cartridge further comprises an outlet conduit for dispensing the fluid, wherein the slide valve further translates the pumping chamber conduit to connect with the outlet conduit, wherein the slide valve translates a pumping chamber conduit to connect with the reservoir conduit and the outlet conduit, wherein the piston is configured for translating the pumping chamber conduit to alternatively connect with the reservoir conduit or the outlet conduit, and wherein the actuator assembly is operable for linear actuation of the plunger and of the slide valve, wherein the automatic analyzer comprises:
an actuator assembly for actuation of the plunger and of the slide valve; and
a controller for controlling the operation of the actuator assembly.

Assignees

• Roche Diagnostics Operations Inc

Inventors

• Boehm Christoph
• Kupser Peter
• Oranth Norbert
• Spinke Juergen
• Brueckner Thorsten
• Klein Timo

Classifications

• Y10T436/2575

  Volumetric liquid transfer · CPC title

• Y10T436/119163

  with aspirator of claimed structure · CPC title

• G01F11/021 Primary

  of the piston type (G01F11/04 takes precedence) · CPC title

• A61M5/16809

  by repeated filling and emptying of an intermediate volume (pressure infusion using positive displacement pumps A61M5/142) · CPC title

• A61M5/14216

  Reciprocating piston type · CPC title