Bicyclic-fused heteroaryl or aryl compounds

US10329302B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10329302-B2
Application numberUS-201815862691-A
CountryUS
Kind codeB2
Filing dateJan 5, 2018
Priority dateApr 4, 2014
Publication dateJun 25, 2019
Grant dateJun 25, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

First claim

Opening claim text (preview).

We claim: 1. A method of treating rheumatoid arthritis in a human comprising administering to the human in need of such treatment a therapeutically effective amount of 1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide, or a pharmaceutically acceptable salt thereof. 2. A method of treating rheumatoid arthritis in a patient comprising administering to the patient in need of such treatment a pharmaceutical composition comprising a therapeutically effective amount of 1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable carrier, excipient, or diluent.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • Drugs for immunological or allergic disorders · CPC title

  • Drugs for disorders of the cardiovascular system · CPC title

  • Drugs for disorders of the blood or the extracellular fluid · CPC title

  • Antineoplastic agents · CPC title

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Frequently asked questions

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What does patent US10329302B2 cover?
Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
Who is the assignee on this patent?
Pfizer
What technology area does this patent fall under?
Primary CPC classification A61K31/40. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 25 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).