Compound useful for the treatment of degenerative and inflammatory diseases

US10328081B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10328081-B2
Application numberUS-201715651116-A
CountryUS
Kind codeB2
Filing dateJul 17, 2017
Priority dateJun 26, 2009
Publication dateJun 25, 2019
Grant dateJun 25, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I: or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for the treatment of psoriatic arthritis, comprising: administering to a subject in need thereof an amount of a compound according to Formula I: or a pharmaceutically acceptable salt thereof sufficient to effect said treatment. 2. The method according to claim 1 , wherein the compound is administered in combination with one or more further therapeutic agents selected from agents for the treatment of psoriatic arthritis. 3. The method according to claim 2 , wherein the compound is administered in combination with one further therapeutic agent selected from agents for the treatment of psoriatic arthritis. 4. A method for the treatment of psoriatic arthritis, comprising: administering to a subject in need thereof an amount of a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a pharmaceutically effective amount of a compound according to Formula I: or a pharmaceutically acceptable salt thereof, sufficient to effect said treatment. 5. A method for the treatment of psoriatic arthritis, comprising: administering to a subject in need thereof an amount of a pharmaceutical composition comprising a pharmaceutically acceptable carrier, a pharmaceutically effective amount of a compound according to Formula I: or a pharmaceutically acceptable salt thereof, and a further therapeutic agent, sufficient to effect said treatment. 6. The method according to claim 4 , wherein the pharmaceutical composition is administered in combination with one or more further therapeutic agents selected from agents for the treatment of psoriatic arthritis. 7. The method according to claim 6 , wherein the pharmaceutical composition is administered in combination with one further therapeutic agent selected from agents for the treatment of psoriatic arthritis. 8. The method according to claim 5 , wherein the further therapeutic agent is an agent for the treatment of psoriatic arthritis.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title

  • Immunosuppressants, e.g. drugs for graft rejection · CPC title

  • Immunomodulators · CPC title

  • Drugs for immunological or allergic disorders · CPC title

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Frequently asked questions

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What does patent US10328081B2 cover?
A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I: or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, aut…
Who is the assignee on this patent?
Galapagos Nv
What technology area does this patent fall under?
Primary CPC classification A61K31/541. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 25 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).