Altered microbiome of chronic pelvic pain

US10316368B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10316368-B2
Application numberUS-201715729249-A
CountryUS
Kind codeB2
Filing dateOct 10, 2017
Priority dateApr 2, 2014
Publication dateJun 11, 2019
Grant dateJun 11, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invention provides probiotic formulations containing live bacteria (e.g., from O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis).

First claim

Opening claim text (preview).

We claim: 1. A probiotic formulation comprising at least three species of live bacteria from the genera of bacteria selected from the group consisting of: Odoribacter, Faecalibacterium, Collinsella, Eggerthella, Lactonifactor , and Roseburia , wherein at least two species are selected from the group consisting of: Odoribacter splanchnicus, Collinsella aerofaciens, Eggerthella sinensis, Lactonifactor longoviformis , and Roseburia intestinalis. 2. The probiotic formulation of claim 1 , comprising at least three species selected from the group consisting of: Odoribacter splanchnicus, Faecalibacterium prausnitzii, Collinsella aerofaciens, Eggerthella sinensis, Lactonifactor longoviformis , and Roseburia intestinalis. 3. The probiotic formulation of claim 2 , comprising at least four species selected from the group consisting of: Odoribacter splanchnicus, Faecalibacterium prausnitzii, Collinsella aerofaciens, Eggerthella sinensis, Lactonifactor longoviformis , and Roseburia intestinalis. 4. The probiotic formulation of claim 3 , comprising at least five species selected from the group consisting of: Odoribacter splanchnicus, Faecalibacterium prausnitzii, Collinsella aerofaciens, Eggerthella sinensis, Lactonifactor longoviformis , and Roseburia intestinalis. 5. The probiotic formulation of claim 4 , comprising Odoribacter splanchnicus, Faecalibacterium prausnitzii, Collinsella hella sinensis, Lactonifactor longoviformis , and Roseburia intestinalis. 6. The probiotic formulation of claim 1 , further comprising a capsule formulated for human consumption with the live bacteria contained therein. 7. A kit comprising the probiotic formulation of claim 1 , and a therapeutic agent for the treatment of interstitial cystitis.

Assignees

Inventors

Classifications

  • for diseases caused by alterations of genetic material · CPC title

  • Probiotics (probiotic yeast, e.g. saccharomyces A61K36/06) · CPC title

  • C12Q1/689Primary

    for bacteria · CPC title

  • Probiotics · CPC title

  • Bacteria (therapeutic use of a bacterial protein A61K38/00) · CPC title

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What does patent US10316368B2 cover?
Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invent…
Who is the assignee on this patent?
Univ Northwestern, Univ Illinois, The Board Of Trustees Of The Univ Of Illinoi
What technology area does this patent fall under?
Primary CPC classification C12Q1/689. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 11 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).