Method for producing pseudopolyrotaxane aqueous dispersion

Patent metadata

Field	Value
Publication number	US-10308772-B2
Application number	US-201615540520-A
Country	US
Kind code	B2
Filing date	Jan 8, 2016
Priority date	Jan 9, 2015
Publication date	Jun 4, 2019
Grant date	Jun 4, 2019

Abstract

The present invention provides a method for producing an aqueous dispersion of pseudopolyrotaxane that enables the production, by an industrially advantageous method for an aqueous dispersion of pseudopolyrotaxane in which the inclusion amount of a cyclodextrin does not increase with time and which can provide a crosslinked polyrotaxane having sufficient stretchability and breaking strength. The present invention relates to a method for producing an aqueous dispersion of pseudopolyrotaxane containing pseudopolyrotaxane particles in which a polyethylene glycol is included in a cavity of a cyclodextrin molecule in a skewered manner, the method including: an inclusion step of mixing a polyethylene glycol and a cyclodextrin in an aqueous medium to include the polyethylene glycol in a cavity of a cyclodextrin molecule, wherein in the inclusion step, a basic compound is added.

First claim

The invention claimed is:

1. A method for producing an aqueous dispersion of a pseudopolyrotaxane containing pseudopolyrotaxane particles in which a polyethylene glycol is included in a cavity of a cyclodextrin molecule in a skewered manner,
the method comprising:
an inclusion step of mixing the polyethylene glycol and a molecular cyclodextrin in an aqueous medium to include the polyethylene glycol in the cavity of the cyclodextrin molecule,
wherein the inclusion step includes a mixing step of dissolving the polyethylene glycol and the cyclodextrin in the aqueous medium to prepare a mixed solution, and a cooling step of cooling the mixed solution to precipitate pseudopolyrotaxane particles, and
a basic compound is added after the pseudopolyrotaxane has been precipitated in the cooling step.

2. The method for producing the aqueous dispersion of the pseudopolyrotaxane according to claim 1 ,
wherein the basic compound is added in an amount of 0.1 to 10 times the number of moles of reactive groups at both ends of the polyethylene glycol.

3. The method for producing the aqueous dispersion of the pseudopolyrotaxane according to claim 1 ,
wherein the polyethylene glycol has a mass average molecular weight of 1,000 to 100,000.

4. The method for producing the aqueous dispersion of the pseudopolyrotaxane according to claim 1 ,
wherein a mass ratio of the polyethylene glycol and the cyclodextrin is 1:2 to 1:5.

5. A method for producing a polyrotaxane containing a cyclodextrin, a polyethylene glycol included in a cavity of the cyclodextrin in a skewered manner, and capping groups at both ends of the polyethylene glycol,
the method comprising the steps of:
producing an aqueous dispersion of a pseudopolyrotaxane by the production method according to claim 1 , and
introducing capping groups in an aqueous medium constituting the aqueous dispersion of the pseudopolyrotaxane after the production step.

6. The method for producing the aqueous dispersion of the pseudopolyrotaxane according to claim 1 ,
wherein a temperature in mixing the polyethylene glycol and the cyclodextrin in the aqueous medium is from 50° C. to 100° C.

7. The method according to claim 1 , wherein the molecular cyclodextrin is α-cyclodextrin, β-cyclodextrin, or γ-cyclodextrin.

8. The method according to claim 1 , wherein the basic compound suppresses an increase in an inclusion amount of the cyclodextrin with time in the aqueous dispersion of the pseudopolyrotaxane.

Assignees

• Sumitomo Seika Chemicals
• Advanced Softmaterials Inc

Inventors

• HAYAMIZU Naohisa
• Okazaki Hiroki
• Kimura Akira
• Okazaki Shinya

Classifications

• C08L71/02

  Polyalkylene oxides · CPC title

• C08J3/03 Primary

  in aqueous media · CPC title

• C08J3/005

  Processes for mixing polymers · CPC title

• C08B37/0015

  Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes · CPC title

• C08G2650/04

  End-capping · CPC title