Carbamate/urea derivatives containing piperidin and piperazin rings as H3 receptor inhibitors
US-9216182-B2 · Dec 22, 2015 · US
US10308608B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10308608-B2 |
| Application number | US-201816047179-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 27, 2018 |
| Priority date | Jul 2, 2015 |
| Publication date | Jun 4, 2019 |
| Grant date | Jun 4, 2019 |
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Provided herein are compounds and methods for inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3).
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What is claimed is: 1. A compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof. 2. The compound or salt of claim 1 , having a structure: 3. The compound or salt of claim 1 , having a structure: 4. The compound or salt of claim 1 , having a structure: 5. The compound or salt of claim 1 , having a structure: 6. The compound or salt of claim 1 , having a structure: 7. The compound or salt of claim 1 , having a structure: 8. The compound or salt of claim 1 , having a structure: 9. The compound or salt of claim 1 , having a structure: 10. The compound or salt of claim 1 , having a structure: 11. The compound or salt of claim 1 , having a structure: 12. The compound or salt of claim 1 , having a structure: 13. The compound or salt of claim 1 , having a structure: 14. The compound or salt of claim 1 , having a structure:
Oxygen atoms · CPC title
with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system · CPC title
Nitrogen atoms not forming part of a nitro radical · CPC title
Oxygen atoms · CPC title
attached in position 4 · CPC title
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