Medical carbon monoxide delivery system

Patent metadata

Field	Value
Publication number	US-10300237-B2
Application number	US-201715431086-A
Country	US
Kind code	B2
Filing date	Feb 13, 2017
Priority date	Feb 20, 2013
Publication date	May 28, 2019
Grant date	May 28, 2019

Abstract

A medical carbon monoxide generator provides for a solid carbon material that may be heated at substantially normal atmospheric pressure to provide a source of medical quality carbon monoxide. The heating source may be an electrical filament or laser controllable by a microcontroller to provide accurate delivery rates and amounts. In one embodiment, a replaceable cartridge holding the carbon material may be used.

First claim

What we claim is:

1. An organ transplant container system comprising:
an insulated container for receiving a transplant organ held in a storage liquid;
a carbon monoxide generator assembly attached to the insulated container and communicating with the storage liquid to provide a source of carbon monoxide to the storage liquid by heating a solid state carbon source in atmospheric pressure air wherein the carbon monoxide generator assembly provides a releasably connectable cartridge including a reaction chamber holding the solid state carbon source communicating with the storage liquid; and
a scrubber element communicating with the storage liquid to vent gas from the storage liquid into the scrubber element and to scrub carbon monoxide from the vented gas.

2. The organ transplant container system of claim 1 wherein the carbon monoxide generator provides:
a reaction chamber holding a purified carbon element and providing an ingress port and egress port;
a pump communicating with the ingress port to provide a source of air passing into the reaction chamber and out of the egress port;
an electrically controllable heater element heating the purified carbon element to generate carbon monoxide gas from the reaction of the heated purified carbon with the air of the reaction chamber; and
a respiratory delivery appliance communicating with the egress port to provide carbon monoxide to the insulated container.

3. The organ transplant container system of claim 2 wherein the purified carbon element is at least USP grade pure carbon.

4. The organ transplant container system of claim 2 wherein the electrically controllable heater element is an ohmic resistor in thermal communication with the purified carbon element.

5. The organ transplant container system of claim 2 wherein the electrically controllable heater element is an optical radiation source focused on the purified carbon element.

6. The organ transplant container system of claim 5 wherein the optical radiation source is a solid-state laser.

7. The organ transplant container system of claim 2 further including
a sensor system for monitoring carbon monoxide passing through the egress port; and
an electronic controller receiving a signal from the sensor system to control the electrically controllable heater in response thereto.

8. The medical carbon monoxide generator of claim 7 wherein the electronic controller controls the electrically controllable heater element to provide a predetermined time varying change in carbon monoxide delivered to the respiratory delivery appliance.

9. The medical carbon monoxide generator of claim 7 wherein the electronic controller further records a time record of carbon monoxide delivery through the egress port.

10. The medical carbon monoxide generator of claim 7 wherein the electronic controller determines a total amount of carbon monoxide generated in the reaction chamber during operation of the medical carbon monoxide generator.

11. The medical carbon monoxide generator of claim 7 further including redundant carbon monoxide sensors and wherein the electronic controller uses readings from the carbon monoxide sensors to deduce carbon monoxide concentration in the egress port.

12. The medical carbon monoxide generator of claim 1 wherein the cartridge includes a data communication element communicating with a remainder of the medical carbon monoxide generator system to identify the cartridge for controlling operation of the medical carbon monoxide generator.

13. The medical carbon monoxide generator of claim 12 wherein the electrically controllable heater according to the identification of the cartridge provides at least one of a predetermined schedule of carbon monoxide delivery from the cartridge and a predetermined total production of carbon monoxide from the cartridge.

14. The medical carbon monoxide generator of claim 12 wherein the data communication element includes a memory for storing usage data with respect to the reaction chamber.

15. The medical carbon monoxide generator of claim 2 further including a filter filtering the air received by the pump.

16. The organ transplant container system of claim 1 further comprising:
a delivery line holding a diffusion element providing for an introduction of carbon monoxide gas through the storage liquid; and
a return line holding a liquid filter resisting flow of liquid from the insulated container into the replaceable cartridge.

Assignees

• Wisconsin Alumni Res Found

Inventors

• Gribb Tye Travis
• Bathe Duncan

Classifications

• A61M16/105

  Filters (A61M16/047, A61M16/22 take precedence; water traps A61M16/08) · CPC title

• A61M2202/0233

  Carbon monoxide · CPC title

• A61M2016/1035

  the anaesthetic agent concentration · CPC title

• A61M2205/123

  with incorporated reservoirs · CPC title

• A61M2205/368

  by electromagnetic radiation, e.g. IR waves · CPC title