Medicament delivery device with delivery finish signal delay

Patent metadata

Field	Value
Publication number	US-10300208-B2
Application number	US-201515312239-A
Country	US
Kind code	B2
Filing date	May 5, 2015
Priority date	Jun 5, 2014
Publication date	May 28, 2019
Grant date	May 28, 2019

Abstract

A medicament delivery device is presented having a housing with a distal and a proximal end, the housing being adapted to receive a medicament container with a delivery member or with a connectable delivery member for delivery of a medicament. The device also has a drive mechanism arranged to act on a plunger rod, which plunger rod in turn is arranged to act on the medicament container for providing automatic delivery of the medicament and a hold-release mechanism interactively connected to the drive mechanism for releasing the drive mechanism from a biased position. A delayable signal generating mechanism generates an audible and/or tactile and/or visual signal indicating that the medicament has been completely delivered, which delayable signal generating mechanism is operably connected between said pre-tensioned drive mechanism and said plunger rod.

First claim

The invention claimed is:

1. A medicament delivery device extending along a longitudinal axis and comprising:
a housing having a distal and a proximal end, said housing being adapted to receive a medicament container;
a drive mechanism comprising a plunger rod driver movable in said housing between biased and released positions and arranged to act on a plunger rod, which plunger rod in turn is arranged to act on the medicament container;
a hold-release mechanism interactively connected to the drive mechanism for holding the drive mechanism in the biased position and releasing the drive mechanism from the biased position; and
a delayable signal generating mechanism comprising a signal generating element interactively connected to the drive mechanism, where
the delayable signal generating mechanism is releasably connected to the hold-release mechanism such that when the plunger rod nears or reaches the end of its operating stroke, the delayable signal generating mechanism is released from the hold-release mechanism whereby the delayable signal generating mechanism is enabled to interact with the drive mechanism for generating an audible and/or tactile and/or visual signal indicating that a medicament has been completely delivered,
wherein said plunger rod driver is operably arranged to said plunger rod via said signal generating element.

2. The medicament delivery device according to claim 1 , wherein said delayable signal generating mechanism comprises a delay element configured to be releasably connected to each other.

3. The medicament delivery device according to claim 2 , wherein said drive mechanism comprises a drive element for biasing the plunger rod driver towards the proximal end of the device.

4. The medicament delivery device according to claim 3 , wherein the signal generating element is connected to the plunger rod driver by a connection configured to restrict a rotational displacement but to allow an axial displacement between said signal generating element and said plunger rod driver.

5. The medicament delivery device according to claim 3 , wherein said delay element is connected to said plunger rod driver by a connection configured to restrict an axial displacement but to allow a rotational displacement between said delay element and said plunger rod driver.

6. The medicament delivery device according to claim 5 , wherein the connection between the delay element and the plunger driver is rotationally damped for regulating the rotational speed of said delay element.

7. The medicament delivery device according to claim 3 , wherein said hold-release mechanism comprises an activation member movable arranged in relation to the housing and having a locking element configured to releasably lock the plunger rod driver, and a blocking member movable arranged in relation to the activation member and configured to prevent the activation member to be actuated before the blocking member is actuated.

8. The medicament delivery device according to claim 7 , wherein said blocking member and said delay element are releasably connected to each other by first guide and hold elements configured to hold the delay element in a non-movable state in relation to the plunger driver when the plunger driver is locked by the locking element of the activation member and to guide the displacement of the delay element towards the proximal end of the device when the plunger driver is released by the activation member such that the displacement of the delay element is an axial displacement in relation to the blocking member.

9. A medicament delivery device according to claim 8 , wherein said delay element and said signal generating element are releasably connected to each other by second guide and hold elements configured:
to hold the signal generating element and said delay element in a non-displaceable state in relation to each other when the delay element together with the plunger driver are axially displaced in relation to the blocking member towards the proximal end of the device;
to promote a rotational displacement of the delay element in relation to the signal generating element when the delay element is released from the blocking member; and
to guide an axial displacement of the signal generating element in relation to the delay element towards the distal end of the device when the signal generating element is released from the delay element whereby the delay element together with the plunger driver continue to be axially displaced in relation to the blocking member towards the proximal end of the device such that a distal end surface of the signal generating element hits a proximal end surface of the plunger driver whereby the audible and/or tactile and/or visual signal indication that a medicament has been completely delivered is generated.

10. The medicament delivery device according to claim 9 , wherein the rotational displacement of the delay element in relation to the signal generating element is rotationally damped by a viscous media arranged between the delay element and the signal generating element.

11. The medicament delivery device according to claim 9 , wherein said second guide and hold elements comprise guide tracks and a central radially extending protrusion arranged on the outer circumferential surface of said signal generating element and a radial inwardly extending protrusion arranged on the inner circumferential surface of said delay member.

12. The medicament delivery device according to claim 11 , wherein the central radially extending protrusion arranged on the outer circumferential surface of said signal generating element comprises an inclined side surface and the radial inwardly extending protrusion arranged on the inner circumferential surface of said delay member comprises an inclination side surface such that said side surfaces configured to promote a rotational displacement of the delay element in relation to the signal generating element.

13. The medicament delivery device according to claim 8 , wherein the housing comprises a proximal housing part and a main housing part which are releasably connected to each other.

14. The medicament delivery device according to claim 13 , further comprising a biased delivery member shield positioned at least partially and axially movable within the housing, said biased delivery member shield being operably connected to the hold-release mechanism such that when said biased delivery member shield is pressed against a delivery site said hold-release mechanism is actuated.

15. The medicament delivery device according to claim 14 , wherein a signal generating element spring is arranged between a proximally directed end wall at the proximal end of the plunger rod driver and a distally directed surface of the circular end plate inside the signal generating element and configured to be compressed during medicament delivery.

16. The medicament delivery device according to claim 15 , wherein the medicament delivery member shield is interactively connected to the delay element by a connection configured to allow a rotation the delay element in relation to the signal generating element after the medicament has been delivered and the housing parts are rotated in relation to each other such that when the housing parts are separated the signal generating element is axially displaced towards the proximal end of the device by the force of the signal generating element spring.

17. The medicament delivery device according to claim 16 , wherein the medicament delivery member shield comprises elongated ledges on the inner surface of the medicament d

Assignees

• Carebay Europe Ltd
• Shl Medical Ag

Inventors

• Gylleby Stefan
• Sall Daniel

Classifications

• A61M2005/202

  cocking means, e.g. to bias the main drive spring of an injector · CPC title

• A61M2205/582

  by tactile feedback · CPC title

• A61M2005/3125

  specific display means, e.g. to indicate dose setting · CPC title

• A61M2005/208

  Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin · CPC title

• A61M5/31581

  performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle · CPC title