System and method for mass spectrometry imaging
US-2024389905-A1 · Nov 28, 2024 · US
US10295498B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10295498-B2 |
| Application number | US-201515116753-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 18, 2015 |
| Priority date | Sep 4, 2014 |
| Publication date | May 21, 2019 |
| Grant date | May 21, 2019 |
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Embodiments of the present invention provide an air dryer for an ion mobility spectrometer, comprising a heating element used to heat a thermal conduction device, thereby heating the desiccant. Embodiments of the present invention further provide a regeneration method, by which the operation mode of the ion mobility spectrometer may be switched, so that during a non-working time of the ion mobility spectrometer, the desiccant is heated and thereby regenerated. With the present invention, the desiccant is avoided from being regularly replaced, thereby improving the performance and increasing the service life of the dryer. Regeneration of the desiccant is performed by making full use of the non-working time of the ion mobility spectrometer without affecting normal operation of instrument.
Opening claim text (preview).
What is claimed is: 1. An air dryer for an ion mobility spectrometer, comprising: a housing; a gas inlet provided in the housing, through which air enters the air dryer; a gas outlet provided in the housing, the gas outlet communicating with an ion migration tube of the ion mobility spectrometer so that dried air enters the ion migration tube through the gas outlet; a desiccant chamber disposed within the housing, a desiccant being arranged within the desiccant chamber to dry the air entering through the gas inlet; a thermal conduction device disposed within the desiccant chamber and surrounded by the desiccant; and a heating element disposed within an interior portion of the thermal conduction device and configured to heat thermal conduction device, wherein the interior portion of the thermal conduction device is isolated from the air. 2. The air dryer according to claim 1 , further comprising: a water cooling device configured to cool the air dryer; a water cooling connection port provided in the housing, through which cooling water from the water cooling device flows into the air dryer and through which the cooling water flows out of the air dryer to return to the water cooling device; and a cooling water passage arranged within the housing, the cooling water flowing through the cooling water passage. 3. The air dryer according to claim 2 , wherein the housing comprises an end cover, which is connected with a body of the housing in a sealed way and on which the gas inlet, the gas outlet and the water cooling connection port are provided. 4. The air dryer according to claim 1 , further comprising: a thermal insulating layer disposed between the housing and the desiccant chamber. 5. The air dryer according to claim 1 , wherein helical fins are provided on a surface of the thermal conduction device. 6. The air dryer according to claim 1 , wherein the desiccant is a molecular sieve. 7. The air dryer according to claim 1 , wherein the housing is cylindrical and the desiccant chamber is cylindrical. 8. An ion mobility spectrometer, comprising the air dryer of claim 1 . 9. A method of regenerating a gas desiccant in an air dryer, the air dryer being the air dryer of claim 1 and used for the ion mobility spectrometer, the method comprising steps of: heating up the heating element to heat the desiccant during a non-working time of the ion mobility spectrometer; inputting air into the dryer while heating the desiccant; and stopping heating after heating the desiccant for a predefined time. 10. The method according to claim 9 , further comprising a step of: cooling the air dryer by a cooling device after stopping heating. 11. The method according to claim 9 , wherein the heating element is heated up to a temperature in a range of 150° C.˜400° C. 12. The method according to claim 11 , wherein the heating element is heated up within 30 minutes and is kept at 400° C. 13. The method according to claim 9 , wherein the predefined time used to heat is in a range of 30 minutes to 2 hours. 14. The method according to claim 10 , wherein in the step of cooling the air dryer by the cooling device, the cooling device is configured to reduce a temperature of the air dryer to an operating allowable temperature within 2 hours.
Cooling or heating systems · CPC title
Ion mobility spectrometry · CPC title
by adsorption · CPC title
Water · CPC title
using hot gas · CPC title
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