Non human animal model for ulcerative colitis and its main complications
US-9217156-B2 · Dec 22, 2015 · US
Composition for prevention or treatment of bronchial asthma comprising PKR inhibitor as active ingredient
US10292969B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10292969-B2 |
| Application number | US-201515547030-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 16, 2015 |
| Priority date | Feb 12, 2015 |
| Publication date | May 21, 2019 |
| Grant date | May 21, 2019 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention relates to a composition for prevention or treatment of bronchial asthma comprising a PKR inhibitor as an active ingredient. The PKR inhibitor and derivatives thereof according to the present invention can be used as a pharmaceutical for prevention, amelioration or treatment of bronchial asthma and as a supplementary health food because the PKR inhibitor and derivatives thereof reduce the total counts of inflammatory cells, eosinophils, neutrophils and lymphocytes in bronchoalveolar lavage fluid of neutrophilic severe asthma-induced mice, reduce airway inflammation and airway hyper-responsiveness, and reduce inflammatory mediators.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for treating bronchial asthma comprising administering the compound represented by the following formula 1: 2. The method according to claim 1 , wherein the bronchial asthma is severe or acute. 3. The method according to claim 1 , wherein the compound reduces the number of inflammatory cells, eosinophils, neutrophils, and lymphocytes caused by asthma. 4. The method according to claim 1 , wherein the compound reduces peribronchitis and perivascular inflammation caused by asthma.
Assignees
Inventors
Classifications
Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title
Foods or foodstuffs containing additives (containing additives for modifying the nutritive qualities A23L33/10; containing substantially indigestive additives, e.g. dietary fibres, A23L33/21; containing additives for preservation A23B); Preparation or treatment thereof · CPC title
- A61K31/429Primary
condensed with heterocyclic ring systems · CPC title
using additives (addition of substantially indigestible substances A23L33/21) · CPC title
Antiasthmatics · CPC title
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- What does patent US10292969B2 cover?
- The present invention relates to a composition for prevention or treatment of bronchial asthma comprising a PKR inhibitor as an active ingredient. The PKR inhibitor and derivatives thereof according to the present invention can be used as a pharmaceutical for prevention, amelioration or treatment of bronchial asthma and as a supplementary health food because the PKR inhibitor and derivatives th…
- Who is the assignee on this patent?
- Nat Univ Chonbuk Ind Coop Found, Chonbuk National Univ Hospital, Undustrial Cooperation Foundation Chonbuk National Univ
- What technology area does this patent fall under?
- Primary CPC classification A61K31/429. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).