Device for optimization of sleep apnea syndrome therapy by kinesthetic stimulation

Patent metadata

Field	Value
Publication number	US-10292898-B2
Application number	US-201514961403-A
Country	US
Kind code	B2
Filing date	Dec 7, 2015
Priority date	Dec 8, 2014
Publication date	May 21, 2019
Grant date	May 21, 2019

Abstract

A device includes a processor configured to detect a respiratory disorder episode and generate kinesthetic stimulation control signals in response to the detection of a respiratory disorder episode. The device further includes at least one kinesthetic effector adapted to be applied to a patient's outer skin site and includes a vibrating electromechanical transducer capable of receiving stimulation control signals and outputting a kinesthetic stimulation energy determined by the stimulation control signals. The processor is further configured to determine the effectiveness of stimulation by detecting a cessation of the respiratory disorder episode. The processor is further configured to determine a stimulation energy by selecting an initial energy value and varying the energy value as a function of the effectiveness of previous stimulation.

First claim

What is claimed is:

1. An optimization device for treatment of a respiratory disorder of a patient by stimulation, including:
a processor configured to detect a respiratory disorder episode;
wherein the processor is further configured to produce kinesthetic stimulation control signals in response to detection of the respiratory disorder episode, wherein the kinesthetic stimulation control signals are associated with a kinesthetic stimulation energy value; and
at least one effector adapted to receive the stimulation control signals and to deliver the kinesthetic stimulation energy value determined by the kinesthetic stimulation control signals;
wherein the processor is further configured to determine an effectiveness of the stimulation energy by detecting a cessation of the respiratory disorder episode;
wherein the processor is further configured to determine the kinesthetic stimulation energy by:
for a first episode, selecting an initial energy value depending on physiological parameters of the patient, and
for a subsequent episode, selecting a starting energy value and varying the energy value depending on the effectiveness of stimulation for a previous episode, the energy value being capped at a maximum value,

wherein the processor is further configured to update the maximum value of the energy value following the subsequent episode such that the energy value remains at a therapeutic level to treat the respiratory disorder while limiting an occurrence of awakenings of the patient.

2. The device of claim 1 , wherein the processor is further configured to determine the kinesthetic stimulation energy by, for a subsequent episode, determining the starting energy value based on an effective energy value having actually stopped the respiratory disorder episode during a previous episode.

3. The device of claim 1 , wherein the maximum value is based on a variable value function of at least one of the patient's sex, the patient's age, the patient's body mass index (BMI), the patient's sleep stage, or a type of respiratory disorder that affects the patient.

4. The device of claim 1 , wherein the processor is further configured to determine the kinesthetic stimulation energy by incrementally raising the energy value from the initial or starting energy value, as long as the respiratory disorder episode does not cease.

5. The device of claim 4 , wherein the processor is further configured to determine the kinesthetic stimulation energy by comparing each incrementally raised energy value to the maximum value.

6. The device of claim 5 , wherein the processor is further configured to determine the kinesthetic stimulation energy by raising the energy value greater than the maximum value when a severe episode of the respiratory disorder is detected.

7. The device of claim 6 , wherein the processor is further configured to set a new value if after raising the energy value greater than the maximum value, the patient is not awakened.

8. The device of claim 1 , wherein the processor is further configured to determine the kinesthetic stimulation energy by, for the first episode, selecting the initial energy value from an initial energy value table for different combinations of at least gender, age, height, weight, and a detected or selected type of respiratory disorder.

9. The device of claim 1 , wherein the at least one effector comprises at least one kinesthetic effector adapted to be applied to a patient's external skin site and comprising a vibrating electromechanical transducer.

10. The device of claim 1 , wherein the first episode is a first episode occurring during a first time period during which the patient is sleeping.

11. The device of claim 10 , wherein the time period during which the patient is sleeping is a night during which the patient is sleeping.

12. The device of claim 10 , wherein the subsequent episode occurs during a subsequent time period during which the patient is sleeping and the previous episode is an episode that occurred during a previous time period during which the patient was sleeping.

Assignees

• Sorin Crm Sas
• Inserm Institut De La Rech Medicale
• Univ Joseph Fourier
• Univ Rennes

Inventors

• Amblard Amel
• Graindorge Laurence
• Feuerstein Delphine
• Hernandez Alfredo
• Pépin Jean-Louis

Classifications

• A61B5/4818 Primary

  Sleep apnoea · CPC title

• A61H2201/5007

  computer controlled · CPC title

• A61M2205/505

  Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches · CPC title

• A61M21/02

  for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia (for massage A61H; electrotherapy A61N, e.g. applying alternating or intermittent electric currents for producing anaesthesia A61N1/36021) · CPC title

• A61H2205/027

  Ears · CPC title