Sulfonamide derivative or pharmaceutically acceptable acid addition salt thereof
US-2016362376-A1 · Dec 15, 2016 · US
Substituted piperidine compound and use thereof
US10287305B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10287305-B2 |
| Application number | US-201715421702-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 1, 2017 |
| Priority date | Feb 4, 2016 |
| Publication date | May 14, 2019 |
| Grant date | May 14, 2019 |
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- Title
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Abstract
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Provided is a substituted piperidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as a prophylactic or therapeutic agent for narcolepsy.
First claim
Opening claim text (preview).
The invention claimed is: 1. Methyl (2R,3S)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or N-((2R,3S)-1-glycoloyl-2-(((cis-4-(2,3,6-trifluorophenyl)cyclohexyl)oxy)methyl)piperidin-3-yl)methanesulfonamide, or a salt thereof. 2. Methyl (2R,3S)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or a salt thereof. 3. N-((2R,3S)-1-glycoloyl-2-(((cis-4-(2,3,6-trifluorophenyl)cyclohexyl)oxy)methyl)piperidin-3-yl)methanesulfonamide or a salt thereof.
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Classifications
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
- C07D211/36Primary
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms · CPC title
- C07D211/56Primary
Nitrogen atoms (nitro radicals C07D211/38) · CPC title
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Frequently asked questions
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- What does patent US10287305B2 cover?
- Provided is a substituted piperidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as a prophylactic or therapeutic agent for narcolepsy.
- Who is the assignee on this patent?
- Takeda Pharmaceuticals Co
- What technology area does this patent fall under?
- Primary CPC classification C07D211/36. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).