Histone deacetylase inhibitors
US-9908899-B2 · Mar 6, 2018 · US
US10280182B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10280182-B2 |
| Application number | US-201816046382-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 26, 2018 |
| Priority date | Feb 28, 2011 |
| Publication date | May 7, 2019 |
| Grant date | May 7, 2019 |
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This invention relates to generally inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3).
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We claim: 1. A compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof. 2. The compound or salt of claim 1 , having a structure: 3. The compound or salt of claim 1 , having a structure: 4. The compound or salt of claim 1 , having a structure: 5. The compound or salt of claim 1 , having a structure: 6. The compound or salt of claim 1 , having a structure: 7. The compound or salt of claim 1 , having a structure: 8. The compound or salt of claim 1 , having a structure: 9. The compound or salt of claim 1 , having a structure: 10. The compound or salt of claim 1 , having a structure:
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms · CPC title
Z being doubly bound oxygen or doubly bound nitrogen, which nitrogen is part of a possibly substituted oximino radical · CPC title
with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals · CPC title
Ortho-condensed systems · CPC title
Ortho-condensed systems · CPC title
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