Electrospinning device and method for applying polymer to tissue

Patent metadata

Field	Value
Publication number	US-10278685-B2
Application number	US-201615072391-A
Country	US
Kind code	B2
Filing date	Mar 17, 2016
Priority date	Apr 1, 2015
Publication date	May 7, 2019
Grant date	May 7, 2019

Abstract

An electrosurgical electrospinning device is presented including a reservoir having a polymer solution disposed therein, the reservoir cooperating with a dispensing apparatus configured to dispense the polymer solution from the reservoir. The electrosurgical electrospinning device further includes a plurality of nozzles connected to the reservoir, each nozzle of the plurality of nozzles including a plurality of needles and a blow-spraying mechanism for blowing gas around each nozzle of the plurality of nozzles when the polymer solution is dispensed from the plurality of needles. The gas from the blow-spraying mechanism and the polymer solution from the plurality of needles are coaxially applied directly onto tissue at voltages of less than or equal to 3 kV.

First claim

The invention claimed is:

1. An electrosurgical electrospinning device, comprising:
a reservoir having a polymer solution disposed therein, the reservoir cooperating with a dispensing apparatus configured to dispense the polymer solution from the reservoir;
a plurality of nozzles connected to the reservoir, each nozzle of the plurality of nozzles including a plurality of needles; and
a blow-spraying mechanism for blowing gas around each nozzle of the plurality of nozzles when the polymer solution is dispensed from the plurality of needles;
wherein the blow-spraying mechanism and the plurality of nozzles are configured to coaxially apply the gas from the blow-spraying mechanism and the polymer solution from the plurality of needles directly onto tissue at voltages of less than or equal to 3 kV.

2. The electrosurgical electrospinning device according to claim 1 , wherein the electrosurgical electrospinning device includes a flexible catheter connected to a body portion, the flexible catheter including the plurality of nozzles therein.

3. The electrosurgical electrospinning device according to claim 2 , wherein the flexible catheter includes a proximal end and a distal end, and wherein the plurality of nozzles are positioned a predetermined distance away from the distal end of the flexible catheter, thus defining a space between the distal end of the catheter and the plurality of nozzles.

4. The electrosurgical electrospinning device according to claim 3 , wherein the predetermined distance is approximately 8 mm to 15 mm.

5. The electrosurgical electrospinning device according to claim 3 , wherein the plurality of nozzles are configured to be repositioned within the flexible catheter to adjust a distance between the plurality of nozzles and a distal end of the flexible catheter.

6. The electrosurgical electrospinning device according to claim 5 , wherein the distance adjustment is approximately between 8 mm and 15 mm.

7. The electrosurgical electrospinning device according to claim 1 , wherein the plurality of needles is configured to deposit a mixture of nano-scale and large-scale fibers onto tissue.

8. The electrosurgical electrospinning device according to claim 7 , wherein a deposition distance of the nano-scale and large-scale fibers is approximately between 25 mm and 100 mm.

9. The electrosurgical electrospinning device according to claim 1 , wherein the plurality of nozzles are arranged in a linear configuration.

10. The electrosurgical electrospinning device according to claim 1 , wherein the plurality of nozzles are arranged in a circular configuration.

11. The electrosurgical electrospinning device according to claim 1 , wherein the plurality of nozzles are arranged as an array.

12. The electrosurgical electrospinning device according to claim 1 , wherein the electrospinning device operates at a voltage approximately between 2 kV and 2.98 kV.

13. The electrosurgical electrospinning device according to claim 1 , wherein the electrosurgical electrospinning device is a handheld device.

14. The electrosurgical electrospinning device according to claim 1 , wherein the electrosurgical electrospinning device is a handheld device including a shaft connected to a handle portion at a proximal end thereof, the shaft incorporating the electrosurgical electrospinning device at a distal end thereof.

15. The electrosurgical electrospinning device according to claim 1 , wherein a select number of nozzles of the plurality of nozzles and a select number of needles of the plurality of needles are deactivated during one or more surgical procedures.

16. The electrosurgical electrospinning device according to claim 1 , wherein electrospinning occurs in a far field regime.

17. An electro surgical electrospinning method performed by an electrosurgical electrospinning device, the method comprising:
dispensing polymer solution from a reservoir via a dispensing apparatus;
connecting a plurality of nozzles to the reservoir, each nozzle of the plurality of nozzles including a plurality of needles;
blowing gas, via a blow-spraying mechanism, around each nozzle of the plurality of nozzles when the polymer solution is dispensed from the plurality of needles; and
coaxially applying the gas from the blow-spraying mechanism and the polymer solution from the plurality of needles directly onto tissue at voltages of less than or equal to 3 kV.

18. The method according to claim 17 , wherein the electrosurgical electrospinning device is a handheld device including a shaft connected to a handle portion at a proximal end thereof, the shaft incorporating the electrosurgical electrospinning device at a distal end thereof.

19. The method according to claim 17 , further comprising operating the electrosurgical electrospinning device at a voltage approximately between 2 kV and 2.98 kV.

20. The method according to claim 17 , further comprising depositing nano-scale and large-scale fibers onto tissue from a distance of approximately between 25 mm and 100 mm.

Assignees

• Covidien Lp

Inventors

• Zaballa Vincent
• Friedrichs Daniel A

Classifications

• A61B17/00491

  Surgical glue applicators · CPC title

• A61B2017/00004

  (bio)absorbable, (bio)resorbable or resorptive · CPC title

• A61B2017/00659

  located only on one side of the opening · CPC title

• D01D5/0084

  Coating by electro-spinning, i.e. the electro-spun fibres are not removed from the collecting device but remain integral with it, e.g. coating of prostheses · CPC title

• A61B2017/00951

  adhesive · CPC title