Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

Patent metadata

Field	Value
Publication number	US-10272060-B2
Application number	US-201815889961-A
Country	US
Kind code	B2
Filing date	Feb 6, 2018
Priority date	Jul 21, 2011
Publication date	Apr 30, 2019
Grant date	Apr 30, 2019

Abstract

The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.

First claim

What is claimed:

1. A vegetable oil comprising omega-3 polyunsaturated fatty acids which comprise docosahexaenoic acid and eicosapentaenoic acid in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of eicosapentaenoic acid, by weight, is from about 19% to about 55% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 35% to about 71% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

2. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 19% to about 43% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 35% to about 47% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

3. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 27% to about 54% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 36% to about 63% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

4. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 26% to about 38% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 52% to about 64% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

5. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 28% to about 36% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 54% to about 62% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

6. A vegetable oil comprising omega-3 polyunsaturated fatty acids which comprise DHA and EPA in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, and DPA n-3 is in an amount of from about 0% to about 10%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of EPA, by weight, is from about 28% to about 36% of the total amount of DHA and EPA, and the amount of DHA, by weight, is from about 54% to about 62% of the total amount of DHA and EPA, wherein said vegetable oil further comprising an effective amount of at least one added antioxidant.

7. A vegetable oil comprises omega-3 polyunsaturated fatty acids which comprise DHA and EPA in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, and DPA n-3 is in an amount of from about 0% to about 2%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of EPA, by weight, is from about 10% to about 25% of the total amount of DHA and EPA, and the amount of DHA, by weight, is from about 75% to about 90% of the total amount of DHA and EPA, wherein said vegetable oil further comprising an effective amount of at least one added antioxidant.

Assignees

• Dsm Ip Assets Bv

Inventors

• Apt Kirk E
• Behrens Paul Warren
• Hansen Jon Milton
• Pfeifer Iii Joseph W
• Stahl Tracey Lynn
• Zirkle Ross

Classifications

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61K31/202 Primary

  having three or more double bonds, e.g. linolenic (eicosanoids, e.g. leukotrienes A61K31/557) · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A23K50/80

  for aquatic animals, e.g. fish, crustaceans or molluscs · CPC title

• A23L33/40

  Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula · CPC title